Evidence map›Paper›PMID 41644823›Full record

ArticleEuropean journal of clinical nutrition2026

Progressive increase of cardiometabolic risk in Brazilian children according to obesity phenotypes.

Bruna Clemente Cota, Mariana de Santis Filgueiras, Nalva de Paula Dias, Leidjaira Lopes Juvanhol, Patrícia Feliciano Pereira, Juliana Farias de Novaes

Abstract read
In one paragraph

Article in European journal of clinical nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Bruna Clemente CotaDepartment of Nutrition and Health, Universidade Federal de Viçosa (UFV), Av. P.H. Rolfs s/n, Campus Universitário, Viçosa, Minas Gerais, Brazil. brunaclementec@gmail.com.ORCID http://orcid.org/0000-0002-3733-5125
Mariana de Santis FilgueirasDepartment of Nutrition and Health, Universidade Federal de Viçosa (UFV), Av. P.H. Rolfs s/n, Campus Universitário, Viçosa, Minas Gerais, Brazil.ORCID http://orcid.org/0000-0003-1932-6126
Nalva de Paula DiasDepartment of Nutrition and Health, Universidade Federal de Viçosa (UFV), Av. P.H. Rolfs s/n, Campus Universitário, Viçosa, Minas Gerais, Brazil.ORCID http://orcid.org/0009-0007-5179-2908
Leidjaira Lopes JuvanholInstituto de Saúde Coletiva, Universidade Federal do Estado do Rio de Janeiro (Unirio), Rio de Janeiro, RJ, Brazil.ORCID http://orcid.org/0000-0001-8012-6006
Patrícia Feliciano PereiraDepartment of Nutrition and Health, Universidade Federal de Viçosa (UFV), Av. P.H. Rolfs s/n, Campus Universitário, Viçosa, Minas Gerais, Brazil.ORCID http://orcid.org/0000-0001-6103-2944
Juliana Farias de NovaesDepartment of Nutrition and Health, Universidade Federal de Viçosa (UFV), Av. P.H. Rolfs s/n, Campus Universitário, Viçosa, Minas Gerais, Brazil.ORCID http://orcid.org/0000-0003-3616-5096

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveWe investigated the association of obesity phenotypes with MetS and components scores, subclinical inflammation, anti- and oxidative markers in children. SUBJECTS/

methodsThis is a cross-sectional study with 364 children (8 and 9-year-olds) in Viçosa, Minas Gerais, Brazil. Children were classified as: 1."normal-weight lean" (NWL) when they had normal-weight by BMI and adequate fat percentage assessed by DXA; 2. "normal-weight obesity" (NWO) for those with normal-weight and excess fat; and 3. "excess weight" for those with overweight/obesity and excess fat. The score for the MetS and its components was estimated, and the inflammatory and oxidative stress markers were measured. Multiple linear regression was used.

resultsOf thirteen cardiometabolic risk factors investigated, five were positively associated with the NWO, compared to NWL. Moreover, eleven cardiometabolic risk factors were associated with excess weight, compared to NWL. When the two phenotypes of excess body fat were contrasted, we found eight cardiometabolic risk factors associated with excess weight, compared to NWO.

conclusionAn intermediate cardiometabolic risk was observed in children with the NWO phenotype when comparing the status of NWL to excess weight. This study reinforces the importance of investigating cardiometabolic risk in early ages, independent of BMI.

Indexed as

Cardiometabolic Risk FactorsCardiovascular DiseasesMetabolic SyndromeObesityPediatric ObesityBiomarkersBody Mass IndexBrazilChildCross-Sectional StudiesFemaleHumansMaleOverweightOxidative StressPhenotypeBiomarkers

Identifiers

PMID41644823
PMCPMC13008770

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