Evidence map›Paper›PMID 41644657›Full record

ArticleScientific reports2026

Genomic profiling of extended-spectrum beta-lactamase-producing Escherichia coli isolated from poultry and poultry farm workers in Accra, Ghana.

Isaac J Okyere, Grace O Semevor, Anthony Ablordey, Sherry Johnson, Eric S Donkor

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PubMed Full text at PMC Publisher
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Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Isaac J OkyereDepartment of Medical Microbiology, University of Ghana Medical School, Korle Bu, P.O. Box KB 4236, Accra, Ghana.
Grace O SemevorDepartment of Medical Microbiology, University of Ghana Medical School, Korle Bu, P.O. Box KB 4236, Accra, Ghana.
Anthony AblordeyDepartment of Bacteriology, Noguchi Memorial Institute for Medical Research, University of Ghana, P.O. Box LG 581, Accra, Ghana.
Sherry JohnsonSchool of Veterinary Medicine, College of Basic and Applied Sciences, University of Ghana, P.O. Box LG 68, Accra, Ghana.
Eric S DonkorDepartment of Medical Microbiology, University of Ghana Medical School, Korle Bu, P.O. Box KB 4236, Accra, Ghana. esampane-donkor@ug.edu.gh.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antimicrobial resistance (AMR), driven by the extensive use of antibiotics in human and animal health, poses a significant global threat. In Ghana, the contribution of poultry farming to the high prevalence of AMR remains underexplored. This study investigates the genomic characteristics and prevalence of extended-spectrum beta-lactamase (ESBL)-producing Escherichia coli in poultry and human populations. A total of 300 cloacal swabs from poultry and 60 stool samples from poultry farm workers in peri-urban Accra were collected from 20 poultry farms and cultured. Bacterial isolates were identified through MALDI-TOF-MS, with ESBL production confirmed using the double disk synergy test. Whole-genome sequencing of 17 multi-drug resistant isolates selected was conducted on the MiSeq Illumina platform to characterize resistance genes, virulence genes, and sequence types. ESBL production was detected in 84.8% (n = 123/145) in isolates from poultry and 67.5% (n = 27/40) in isolates from humans. All isolates were resistant to cefotaxime, with significant resistance to tetracycline and sulfamethoxazole-trimethoprim also recorded. The bla

Indexed as

beta-LactamasesEscherichia coliEscherichia coli InfectionsPoultryAnimalsAnti-Bacterial AgentsDrug Resistance, Multiple, BacterialFarmersFecesGenome, BacterialGhanaHumansMicrobial Sensitivity TestsThird Generation CephalosporinsWhole Genome SequencingAnti-Bacterial Agentsbeta-LactamasesThird Generation CephalosporinsAntimicrobial resistanceEscherichia coliExtended-spectrum beta-lactamaseGhanaPoultry farmingWhole-genome sequencing

Identifiers

PMID41644657
PMCPMC12929682

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.