Evidence map›Paper›PMID 41644186›Full record

ArticleBMJ paediatrics open2026

Children with suspected anterior cutaneous nerve entrapment syndrome (ACNES), it's not all the abdominal wall.

Tom de Leeuw, Anke Top, Bernadette de Mol, Petra Honig-Mazer, Ramon Gorter, Robert Jan Stolker, Maaike Dirckx, Saskia N de Wildt

Abstract read
In one paragraph

Article in BMJ paediatrics open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Tom de LeeuwAnesthesiology and Pain Medicine, Erasmus MC Sophia Children Hospital, Rotterdam, The Netherlands t.deleeuw@erasmusmc.nl.ORCID http://orcid.org/0000-0001-9516-3088
Anke TopAnesthesiology, Amsterdam UMC Locatie AMC, Amsterdam, The Netherlands.
Bernadette de MolCenter for Pain Medicine, Erasmus MC Sophia, Rotterdam, The Netherlands.
Petra Honig-MazerChild and Adolescent Psychiatry/Psychology, Erasmus MC Sophia, Rotterdam, The Netherlands.
Ramon GorterPediatric Surgery, Amsterdam UMC Locatie AMC, Amsterdam, The Netherlands.
Robert Jan StolkerAnesthesiology, Erasmus MC University Medical Center Rotterdam, Rotterdam, The Netherlands.
Maaike DirckxCenter for Pain Medicine, Erasmus MC Sophia, Rotterdam, The Netherlands.
Saskia N de WildtPharmacology & Toxicology, Radboud Universiteit, Nijmegen, The Netherlands.ORCID http://orcid.org/0000-0002-0502-0647

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAnterior cutaneous nerve entrapment syndrome (ACNES) is a chronic pain syndrome that also occurs in children. The European Pain Federation EFIC recommends the application of the biopsychosocial model of pain. In children with suspected ACNES, the use of this model in diagnosis and treatment appears underused. Most publications focus on invasive interventions. These are potentially harming patients due to this one-dimensional approach. We aimed to assess the use of the biopsychosocial model during the diagnosis and treatment of children with chronic abdominal pain and suspected ACNES before referral to a tertiary paediatric pain centre (PPC) and diagnosis and treatment outcomes in the PPC using the biopsychosocial model.

designSingle-centre retrospective cohort study of patients referred to a tertiary PPC with (suspected) diagnosis of ACNES between November 2017 and March 2024. PRIMARY OUTCOME: Use of the biopsychosocial model and treatments performed before referral to the PPC. SECONDARY OUTCOMES: Confirmation of the diagnosis of ACNES on assessment and results of therapeutic interventions performed in the PPC.

results31 patients were included. In less than 25% of the patients, the biopsychosocial model was used before referral. The treatments performed were diverse. At the PCC, in none of the cases could the diagnosis of ACNES be solidly confirmed. After treatment using the biopsychosocial model in the PPC, 20 patients (64.5%) reported less or absence of pain.

conclusionFailure to use the biopsychosocial model in the treatment of suspected ACNES in children might lead to unnecessary invasive interventions with a risk of persistence of pain while the pain-maintaining factors are inadequately addressed. Therefore, a diagnostic-treatment algorithm is proposed.

Indexed as

Abdominal PainAbdominal WallChronic PainNerve Compression SyndromesAdolescentChildFemaleHumansMaleRetrospective StudiesChildPain

Identifiers

PMID41644186
PMCPMC12878369

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