Evidence map›Paper›PMID 41644139›Full record

ArticleThorax2026

Impact of air pollution on lung function in cystic fibrosis over a decade in London: a UK CF Registry study.

Muhammad Saleem Khan, Benjamin Barratt, Bethan Davies, Nicholas J Simmonds, Frédéric B Piel

Abstract read
In one paragraph

Article in Thorax, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Muhammad Saleem KhanUK Small Area Health Statistics Unit, School of Public Health, Faculty of Medicine, Imperial College London, London, UK.ORCID http://orcid.org/0000-0001-6092-2021
Benjamin BarrattNational Institute for Health & Care Research (NIHR) Health Protection Research Unit (HPRU) in Environmental Exposures and Health, Imperial College London, London, UK.ORCID http://orcid.org/0000-0002-5983-0426
Bethan DaviesUK Small Area Health Statistics Unit, School of Public Health, Faculty of Medicine, Imperial College London, London, UK.
Nicholas J SimmondsAdult Cystic Fibrosis Centre, Royal Brompton Hospital, London, UK.
Frédéric B PielUK Small Area Health Statistics Unit, School of Public Health, Faculty of Medicine, Imperial College London, London, UK f.piel@imperial.ac.uk.ORCID http://orcid.org/0000-0001-8131-7728

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveDespite extensive research on the detrimental effects of air pollution on respiratory diseases like asthma and chronic obstructive pulmonary disease, the impact on people with cystic fibrosis (CF) remains understudied. Our study aimed to quantify the association between air pollution exposure and lung function decline in people with CF in London, UK.

methodsUsing 10 years (2008-2017) of UK Cystic Fibrosis Registry data, we conducted a longitudinal cohort study to evaluate the association between air pollution and the rate of decline in percent predicted forced expiratory volume in 1 second (ppFEV

resultsWe used 3333 ppFEV

conclusionsThis study provides novel evidence of the detrimental impact of air pollution on lung function in people with CF. Our findings highlight the importance of addressing air pollution as a modifiable risk factor to improve long-term outcomes of people with CF, and the need for national studies of the impact of environmental factors on CF in the UK.

Indexed as

Air PollutionCystic FibrosisEnvironmental ExposureLungAdolescentAdultAir PollutantsChildChild, PreschoolFemaleForced Expiratory VolumeHumansLondonLongitudinal StudiesMaleNitrogen DioxideAir PollutantsNitrogen DioxideParticulate MatterCystic Fibrosis

Identifiers

PMID41644139
PMCPMC13479626

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.