Evidence map›Paper›PMID 41643900›Full record

ArticleMucosal immunology2026

Expression of CD103 facilitates localization and activation of CD4

Thomas Lindenstrøm, Nafsika Panagiotopoulou, Sara B Cohen, Paula Torres Rodriguez, Joshua S Woodworth, Mari Morikawa, Mehnaz Halima, Camilla Myhre Maymann, Tu Hu, Sylvia M Stull and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Mucosal immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Thomas LindenstrømCenter for Vaccine Research, Department of Infectious Disease Immunology, Statens Serum Institut, Copenhagen, Denmark; Novo Nordisk Foundation Initiative for Vaccines and Immunity, NIVI Research Center, Department of Immunology and Microbiology, University of Copenhagen, Copenhagen, Denmark.
Nafsika PanagiotopoulouCenter for Vaccine Research, Department of Infectious Disease Immunology, Statens Serum Institut, Copenhagen, Denmark; Novo Nordisk Foundation Initiative for Vaccines and Immunity, NIVI Research Center, Department of Immunology and Microbiology, University of Copenhagen, Copenhagen, Denmark.
Sara B CohenSeattle Children's Research Institute, Center for Global Infectious Disease Research, Seattle, WA, USA.
Paula Torres RodriguezCentre of Vaccinology, University of Geneva, Geneva, Switzerland.
Joshua S WoodworthCenter for Vaccine Research, Department of Infectious Disease Immunology, Statens Serum Institut, Copenhagen, Denmark; Novo Nordisk Foundation Initiative for Vaccines and Immunity, NIVI Research Center, Department of Immunology and Microbiology, University of Copenhagen, Copenhagen, Denmark.
Mari MorikawaSeattle Children's Research Institute, Center for Global Infectious Disease Research, Seattle, WA, USA.
Mehnaz HalimaSeattle Children's Research Institute, Center for Global Infectious Disease Research, Seattle, WA, USA.
Camilla Myhre MaymannCenter for Vaccine Research, Department of Infectious Disease Immunology, Statens Serum Institut, Copenhagen, Denmark; Novo Nordisk Foundation Initiative for Vaccines and Immunity, NIVI Research Center, Department of Immunology and Microbiology, University of Copenhagen, Copenhagen, Denmark.
Tu HuCenter for Vaccine Research, Department of Infectious Disease Immunology, Statens Serum Institut, Copenhagen, Denmark; Novo Nordisk Foundation Initiative for Vaccines and Immunity, NIVI Research Center, Department of Immunology and Microbiology, University of Copenhagen, Copenhagen, Denmark.
Sylvia M StullSeattle Children's Research Institute, Center for Global Infectious Disease Research, Seattle, WA, USA.
Anders WoetmannLEO Foundation Skin Immunology Research Center, Department of Immunology and Microbiology, University of Copenhagen, Copenhagen, Denmark.
Peter L AndersenDepartment of Infectious Diseases, Novo Nordisk Foundation, Hellerup, Denmark.
Kevin B UrdahlSeattle Children's Research Institute, Center for Global Infectious Disease Research, Seattle, WA, USA; University of Washington, Department of Pediatrics, Seattle, WA, USA.
Benjamin H GernSeattle Children's Research Institute, Center for Global Infectious Disease Research, Seattle, WA, USA; University of Washington, Department of Pediatrics, Seattle, WA, USA; University of Washington, Department of Global Health, Seattle, WA, USA.
Rasmus MortensenCenter for Vaccine Research, Department of Infectious Disease Immunology, Statens Serum Institut, Copenhagen, Denmark; Novo Nordisk Foundation Initiative for Vaccines and Immunity, NIVI Research Center, Department of Immunology and Microbiology, University of Copenhagen, Copenhagen, Denmark. Electronic address: rjm@ssi.dk.

Funding

IMMUNE MECHANISMS OF PROTECTION AGAINST MYCOBACTERIUM TUBERCULOSIS CENTER (IMPAC-TB) - SARS-CoV-2 RELATED RESEARCH75N93019C00070 · NIAID · SEATTLE CHILDREN'S HOSPITAL · PI URDAHL, KEVIN · 2019 to 2025
$86.6M
Eliciting lung-localized CD4 T cell responses against Mycobacterium tuberculosis in preventive and post-exposure settingsR01AI134246 · NIAID · SEATTLE CHILDREN'S HOSPITAL · PI LINDENSTRØM, THOMAS, URDAHL, KEVIN B · 2017 to 2021
$3.3M
Dissecting the role of vaccine-promoted Th17 cells in protective immunity against tuberculosisR01AI185516 · NIAID · STATENS SERUM INSTITUTE · PI Rasmus Skaarup Mortensen · 2025 to 2026
$1.4M
Dissecting the molecular regulation of T cell localization and function within the Mycobacterium tuberculosis granulomaK08AI166072 · NIAID · SEATTLE CHILDREN'S HOSPITAL · PI Benjamin Henry Gern · 2022 to 2026
$929k
NIAID NIH HHS 75N93019C00070NIAID NIH HHS K08 AI166072NIAID NIH HHS R01 AI134246NIAID NIH HHS R01 AI185516
6 · The paper itself

Abstract

The spatial localization of CD4

Indexed as

CD4-Positive T-LymphocytesEndothelium, VascularLungMycobacterium tuberculosisTuberculosis VaccinesAnimalsAntigens, CDHumansIntegrin alpha ChainsLectins, C-TypeMacaca fascicularisMiceMice, Inbred C57BLReceptors, ImmunologicTh17 Cellsalpha E integrinsAntigens, CDIntegrin alpha ChainsKLRG1 protein, humanLectins, C-TypeReceptors, ImmunologicTuberculosis Vaccines

Identifiers

PMID41643900
PMCPMC13284540

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.