Evidence map›Paper›PMID 41643423›Full record

ArticleBiosensors & bioelectronics2026

Intracellular oxygen measurement in vivo by smartphone readout of endogenous Protoporphyrin IX delayed fluorescence.

Protik Chandra Biswas, Jason R Gunn, Tayyaba Hasan, Brian W Pogue

Abstract read
In one paragraph

Article in Biosensors & bioelectronics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Protik Chandra BiswasThayer School of Engineering, Dartmouth College, Hanover, NH, United States. Electronic address: Protik.Chandra.Biswas@dartmouth.edu.
Jason R GunnThayer School of Engineering, Dartmouth College, Hanover, NH, United States.
Tayyaba HasanMassachusetts General Brigham, Harvard Medical School, Wellman Center for Photomedicine, Boston, MA, United States.
Brian W PogueThayer School of Engineering, Dartmouth College, Hanover, NH, United States. Electronic address: Brian.W.Pogue@dartmouth.edu.

Funding

Small Molecule Enhancers of Photodynamic Therapy for Skin CancerP01CA084203 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI Brian William Pogue · 2001 to 2026
$27.9M
NCI NIH HHS P01 CA084203
6 · The paper itself

Abstract

Direct measurement of mitochondrial oxygen tension in vivo provides direct information on tissue metabolism and could facilitate new approaches in disease detection, function monitoring, and treatment efficacy assessment with cellular level data, with far superior sensitivity to oxygen changes than blood saturation measures. Here, a platform system was engineered to quantify fast sampling of oxygen partial pressure (pO

Indexed as

Biosensing TechniquesOxygenProtoporphyrinsSmartphoneAnimalsEquipment DesignFluorescenceMitochondriaSpectrometry, FluorescenceOxygenprotoporphyrin IXProtoporphyrinsHypoxiaProtoporphyrin IXRolling shutterSmartphoneTime-resolved delayed fluorescenceTissue oxygen sensing

Identifiers

PMID41643423
PMCPMC13343547

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.