Evidence map›Paper›PMID 41643054›Full record

ArticleInternational braz j urol : official journal of the Brazilian Society of Urology

Salvage Single-Port Transvesical Robotic Radical Prostatectomy Following High-Intensity Focused Ultrasound (HIFU) Therapy.

Mohamad Watfa, Nicolas A Soputro, Abdulrahman Al-Bayati, Karim Daher, Salim Younis, Samarpit Rai, Rui M Bernardino, Lin Wang, Zeyad R Schwen, Ruben Olivares and 2 more

Abstract readCase ReportsVideo-Audio Media
PubMed Full text at PMC Publisher
In one paragraph

Article in International braz j urol : official journal of the Brazilian Society of Urology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Mohamad WatfaGlickman Urological Institute, Cleveland Clinic, Ohio, USA.
Nicolas A SoputroGlickman Urological Institute, Cleveland Clinic, Ohio, USA.
Abdulrahman Al-BayatiGlickman Urological Institute, Cleveland Clinic, Ohio, USA.
Karim DaherGlickman Urological Institute, Cleveland Clinic, Ohio, USA.
Salim YounisGlickman Urological Institute, Cleveland Clinic, Ohio, USA.
Samarpit RaiGlickman Urological Institute, Cleveland Clinic, Ohio, USA.
Rui M BernardinoGlickman Urological Institute, Cleveland Clinic, Ohio, USA.
Lin WangGlickman Urological Institute, Cleveland Clinic, Ohio, USA.
Zeyad R SchwenGlickman Urological Institute, Cleveland Clinic, Ohio, USA.
Ruben OlivaresGlickman Urological Institute, Cleveland Clinic, Ohio, USA.
Riccardo AutorinoGlickman Urological Institute, Cleveland Clinic, Ohio, USA.
Jihad KaoukGlickman Urological Institute, Cleveland Clinic, Ohio, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionFocal therapy with high-intensity focused ultrasound (HIFU) has emerged as a treatment option for selected patients with localized prostate cancer; however, disease recurrence requiring salvage intervention remains a recognized challenge (1-5). Salvage radical prostatectomy is technically demanding due to post-ablative tissue changes, which may compromise oncologic and functional outcomes (6,7). Herein, we describe the surgical technique and clinical outcomes of salvage robotic-assisted radical prostatectomy (RARP) performed using a single-port (SP) transvesical approach following HIFU. MATERIALS AND

methodsThe index case was a 57-year-old man with a history of right hemigland HIFU for ISUP Grade Group 2 prostate cancer. During routine surveillance four years after HIFU, his PSA rose to 3.64 ng/mL, prompting repeat biopsy. Biopsy confirmed clinically significant recurrent prostate cancer both within and outside the prior treatment field, with bilateral involvement. Preoperatively, the patient reported satisfactory erectile function, with a Sexual Health Inventory for Men (SHIM) score of 25/25. After informed consent, salvage transvesical SP-RARP was performed. Dissection was carried out with anticipation of post-ablation tissue changes, and bilateral nerve-sparing was incorporated to optimize functional outcomes.

resultsThe procedure was completed in 82 minutes without placement of additional ports and without intraoperative complications. Estimated blood loss was 75 mL. The patient was discharged home the same day (4.3 hours postoperatively). Foley catheter removal on postoperative day 6 was followed by immediate urinary continence. Erectile function remained satisfactory at 3 months, indicating preservation of baseline functional outcomes. Final pathology demonstrated pT3b ISUP Grade Group 2 prostate cancer with evidence of prior ablation and negative surgical margins. At the most recent follow-up (12 months), PSA remained undetectable, with no biochemical recurrence.

conclusionTransvesical SP-RARP appears to be a safe and effective salvage option following focal ablative therapy for prostate cancer. Leveraging the advantages of single-port robotic technology (8,9), this approach may facilitate outpatient surgery while maintaining favorable functional and oncologic outcomes.

Indexed as

High-Intensity Focused Ultrasound AblationProstatectomyProstatic NeoplasmsRobotic Surgical ProceduresSalvage TherapyHumansMaleMiddle AgedNeoplasm Recurrence, LocalTreatment Outcome

Identifiers

PMID41643054
PMCPMC13124183

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.