Evidence map›Paper›PMID 41642987›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2026

Dopaminergic mechanisms supporting hippocampal postencoding dynamics in humans.

Claire J Ciampa, Thomas M Morin, Jourdan H Parent, Alex Adornato, Jordyn L Cowan, Katherine O'Malley, Rachel E Marcus, Charlee Gordon, James D Howard, Arielle Tambini and 3 more

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Claire J CiampaPsychology Department, Brandeis University, Waltham, MA 02153.ORCID 0000-0002-9956-3094
Thomas M MorinPsychology Department, Brandeis University, Waltham, MA 02153.ORCID 0000-0003-4120-0669
Jourdan H ParentPsychology Department, Brandeis University, Waltham, MA 02153.ORCID 0000-0002-0705-3362
Alex AdornatoPsychology Department, Brandeis University, Waltham, MA 02153.
Jordyn L CowanPsychology Department, Brandeis University, Waltham, MA 02153.
Katherine O'MalleyPsychology Department, Brandeis University, Waltham, MA 02153.
Rachel E MarcusPsychology Department, Brandeis University, Waltham, MA 02153.ORCID 0000-0003-0556-0368
Charlee GordonPsychology Department, Brandeis University, Waltham, MA 02153.ORCID 0009-0007-9853-7621
James D HowardPsychology Department, Brandeis University, Waltham, MA 02153.
Arielle TambiniNathan Kline Institute for Psychiatric Research, Orangeburg, NY 10962.ORCID 0000-0001-9200-9165
Cristina CusinDepression Clinical and Research Program, Massachusetts General Hospital, Boston, MA 02114.
Jacob HookerMartinos Center for Biomedical Imaging, Massachusetts General Hospital, Boston, MA 02129.ORCID 0000-0002-9394-7708
Anne S BerryPsychology Department, Brandeis University, Waltham, MA 02153.ORCID 0000-0002-5086-3643

Funding

Age effects on memory and reward systems in decision makingR00AG058748 · NIA · BRANDEIS UNIVERSITY · PI BERRY, ANNE SHIVELY · 2019 to 2021
$745k
Conjoint Effects of Dopamine and Tau on Cognition in AgingF32AG084259 · NIA · MASSACHUSETTS GENERAL HOSPITAL · PI Thomas Morin · 2024 to 2026
$247k
Dopaminergic mechanisms of reward memory in agingF31AG085963 · NIA · BRANDEIS UNIVERSITY · PI CIAMPA, CLAIRE · 2024 to 2025
$72k
HHS | NIH | National Institute on Aging (NIA) F31AG085963HHS | NIH | National Institute on Aging (NIA) F32AG084259HHS | NIH | National Institute on Aging (NIA) R00AG058748NIA NIH HHS F31 AG085963NIA NIH HHS F32 AG084259NIA NIH HHS R00 AG058748
6 · The paper itself

Abstract

Deficits in dopamine function cause alterations in episodic memory. Converging evidence implicates dopamine in postencoding hippocampal mechanisms inferred to support long-term memory, though there is a lack of direct evidence in humans. We address this gap using pharmacological functional MRI (fMRI) and positron emission tomography (PET). Using a motivated reward encoding task on and off oral methylphenidate, we tested whether individual differences in baseline dopamine ([

Indexed as

DopamineHippocampusAgedDopaminergic ImagingFemaleHumansMagnetic Resonance ImagingMaleMemory, EpisodicMethylphenidateMiddle AgedPositron-Emission TomographyRacloprideReceptors, Dopamine D2Receptors, Dopamine D3RewardDopamineMethylphenidateRacloprideReceptors, Dopamine D2Receptors, Dopamine D3agingdopaminereward memorysimultaneous PET/fMRI

Identifiers

PMID41642987
PMCPMC12890984

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.