Synergistic interactions of ruthenium-based carbon monoxide-releasing molecules and antibiotics in their effects on

Salar Ali, Lauren K Wareham, Robert K Poole, Samantha McLean

Abstract read

In one paragraph

Article in Microbiology (Reading, England), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

Exploratory Label-Free Proteomic Profiling of theMicroorganisms · 2026
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Salar AliDepartment of Molecular Biology and Biotechnology, The University of Sheffield, Sheffield, S10 2TN, UK.

Lauren K WarehamDepartment of Ophthalmology and Visual Sciences, Vanderbilt University Medical Center, Nashville, TN 37232, USA.

Robert K PooleDepartment of Molecular Biology and Biotechnology, The University of Sheffield, Sheffield, S10 2TN, UK.

Samantha McLeanSchool of Science and Technology, Nottingham Trent University, Nottingham, NG11 8NS, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The emergence of antibiotic-resistant pathogenic bacteria poses a major and growing public health risk. Because antibiotics act on specific molecular targets, bacteria may evolve resistance mechanisms that alter or bypass these targets. This work investigated the antimicrobial effects of carbon monoxide-releasing molecules (CORMs) and their potential for co-administration with a variety of commonly used antibiotics against

Indexed as

Anti-Bacterial AgentsCarbon MonoxideEscherichia coliOrganometallic CompoundsRutheniumDrug SynergismMicrobial Sensitivity TestsAnti-Bacterial AgentsCarbon MonoxideOrganometallic CompoundsRutheniumtricarbonylchloro(glycinato)ruthenium(II)tricarbonyldichlororuthenium (II) dimerantibioticscarbon monoxidecarbon monoxide-releasing molecules (CORMs)drug interactionsEscherichia coli

Identifiers

PMID41642642

DOI10.1099/mic.0.001669

PMCPMC12877792

What OpenQuestion holds

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LicenceCC BY

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.