Evidence map›Paper›PMID 41642541›Full record

ArticleBiotechnology letters2026

Cellulose microfiber production from green seaweed Ulva lactuca using hydrated deep eutectic solvent.

Rizfi Fariz Pari, Safrina Dyah Hardiningtyas, Wahyu Ramadhan, Uju, Rie Wakabayashi, Masahiro Goto, Noriho Kamiya

Abstract read
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In one paragraph

Article in Biotechnology letters, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Rizfi Fariz PariDepartment of Applied Chemistry, Graduate School of Engineering, Kyushu University, 744 Motooka, Fukuoka, 819-0395, Japan.
Safrina Dyah HardiningtyasDepartment of Aquatic Product Technology, Faculty of Fisheries and Marine Sciences, IPB University, Bogor, 16680, Indonesia.
Wahyu RamadhanDepartment of Aquatic Product Technology, Faculty of Fisheries and Marine Sciences, IPB University, Bogor, 16680, Indonesia.
UjuDepartment of Aquatic Product Technology, Faculty of Fisheries and Marine Sciences, IPB University, Bogor, 16680, Indonesia.
Rie WakabayashiDepartment of Applied Chemistry, Graduate School of Engineering, Kyushu University, 744 Motooka, Fukuoka, 819-0395, Japan.
Masahiro GotoDepartment of Applied Chemistry, Graduate School of Engineering, Kyushu University, 744 Motooka, Fukuoka, 819-0395, Japan.
Noriho KamiyaDepartment of Applied Chemistry, Graduate School of Engineering, Kyushu University, 744 Motooka, Fukuoka, 819-0395, Japan. kamiya.noriho.367@m.kyushu-u.ac.jp.ORCID http://orcid.org/0000-0003-4898-6342

Funding

Direktorat Jenderal Pendidikan Tinggi 069.2/E4.4/KU/2024Japan Society for the Promotion of Science JPJSBP120228101
6 · The paper itself

Abstract

We investigated the effectiveness of hydrated deep eutectic solvents (DESs) to achieve tunable seaweed cellulose microstructures from Ulva lactuca. Cellulose was extracted via a sequential chemical protocol, then treated with 30% DESs (choline chloride (ChCl) or betaine as hydrogen bond acceptors and urea, citric acid, or oxalic acid as donors) combined with mechanical shearing. While most DESs combinations yielded spherical seaweed cellulose microparticles (dry diameter of 605-777 nm), the ChCl:urea formulation successfully produced seaweed cellulose microfibers (SCMFs). These SCMFs exhibited superior quality (dry diameter of 372 nm), and water dispersibility with a hydrodynamic diameter of 134 nm and a polydispersity index of 0.23. Crucially, the DES composition dictated cellulose structure: ChCl:urea-treated SCMF remained predominantly amorphous, whereas other DESs treatments increased microparticles crystallinity. Furthermore, ChCl:oxalic acid introduced carboxyl functional groups. Selecting appropriate hydrated DESs thus offers a sustainable biotechnology tool to tune cellulose morphology, crystallinity, and surface chemistry.

Indexed as

CelluloseDeep Eutectic SolventsSeaweedUlvaCholineEdible SeaweedsUreaCelluloseCholineDeep Eutectic SolventsUreaCellulose microfibersCellulose microparticlesHydrated deep eutectic solventPretreatmentSeaweed biomass

Identifiers

PMID41642541

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.