Evidence map›Paper›PMID 41642469›Full record

ArticleMolecular and cellular biochemistry2026

Mesenchymal stem cell exosomes alleviate ischemic myocardial injury by miR-125b-5p/BTG2 pathway.

Lijun Luo, Lieyou Li, Shuyun Wu, Xinjie Zeng, Lin Fan

Abstract read
PubMed Publisher
In one paragraph

Article in Molecular and cellular biochemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Research progress on BTG2 in non‑tumor diseases (Review).International journal of molecular medicine · 2026
    Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Lijun LuoDepartment of Cardiology, Fujian Cardiovascular Medical Center, Fujian Institute of Coronary Artery Disease, Fujian Medical University Union Hospital, Fuzhou, 350001, China.
Lieyou LiDepartment of Cardiology, Fujian Cardiovascular Medical Center, Fujian Institute of Coronary Artery Disease, Fujian Medical University Union Hospital, Fuzhou, 350001, China.
Shuyun WuDepartment of Cardiology, Fujian Cardiovascular Medical Center, Fujian Institute of Coronary Artery Disease, Fujian Medical University Union Hospital, Fuzhou, 350001, China.
Xinjie ZengDepartment of Cardiology, Fujian Cardiovascular Medical Center, Fujian Institute of Coronary Artery Disease, Fujian Medical University Union Hospital, Fuzhou, 350001, China.
Lin FanDepartment of Cardiology, Fujian Cardiovascular Medical Center, Fujian Institute of Coronary Artery Disease, Fujian Medical University Union Hospital, Fuzhou, 350001, China. rickfan7587@hotmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

MicroRNAs mediate the protective effects of bone marrow mesenchymal stem cell-derived exosomes (BMSC-Exos) against myocardial injury. This study aimed to elucidate the specific role of exosomal miR-125b-5p in ischemic myocardial injury, focusing on its regulatory interaction with B-cell translocation gene 2 (BTG2). Murine BMSCs were transfected with miR-125b-5p inhibitor or negative-control (NC) oligonucleotides and then used to generate miR-125b-5p-knockdown (miR-125b-5p

Indexed as

ExosomesImmediate-Early ProteinsMesenchymal Stem CellsMicroRNAsMyocardial InfarctionMyocardial IschemiaSignal TransductionTumor Suppressor ProteinsAnimalsApoptosisMaleMiceMice, Inbred C57BLBtg2 protein, mouseImmediate-Early ProteinsMicroRNAsMirn125 microRNA, mouseTumor Suppressor ProteinsBTG2CardioprotectionExosomesmiR-125b-5pMyocardial injury

Identifiers

PMID41642469

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.