Evidence map›Paper›PMID 41642361›Full record

Trial reportSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2026

Efficacy of pulsed electromagnetic field therapy on acute radiodermatitis in breast cancer patients: a randomized controlled study.

Mahmoud Hamada Mohamed, Mohamed N Selim, Marwa Elsayed Mohamed, Mohamed Magdy Elmeligie, Ahmed Mahmoud Kadry, Reda Kotb Abdelrazik, Sara Mohamed Samir, Roshdy Mohamed Kamel, Kamaleldin Ahmed Kamal, Mahmoud Elshazly

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06003764 (Efficacy of Pulsed Electromagnetic Field Therapy on Acute Radiodermatitis in Breast Cancer Patients), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06003764 nacompletednot on this map

Efficacy of Pulsed Electromagnetic Field Therapy on Acute Radiodermatitis in Breast Cancer Patients

TypeinterventionalSponsorAhram Canadian UniversityRan2023 to 2025Enrolled50ConditionsDermatitis, Radiation InducedArmsPulsed electromagnetic field, traditional skin care
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Mahmoud Hamada MohamedPhysical Therapy for Integumentary Department, Faculty of Physical Therapy, Benha University, Benha, 13511, Egypt. mahmoud.mohamed@fpt.bu.edu.eg.ORCID http://orcid.org/0000-0002-6248-6021
Mohamed N SelimBasic Science Department, Faculty of Physical Therapy, Beni-Suef University, Beni Suef, Egypt.
Marwa Elsayed MohamedPhysical Therapy for Women and Child Health Department, Faculty of Physical Therapy, Beni Suef University, Beni Suef, Egypt.
Mohamed Magdy ElmeligieBasic Science Department, Faculty of Physical Therapy, Alhayah University, Cairo, Egypt.
Ahmed Mahmoud KadryPhysical Therapy for Integumentary Department, Faculty of Physical Therapy, Kafr Elsheikh University, Kafr Elsheikh, Egypt.
Reda Kotb AbdelrazikPhysical Therapy for Musculoskeletal Disorders and Its Surgery Department, Faculty of Physical Therapy, Benha University, Benha, Egypt.
Sara Mohamed SamirPhysical Therapy for Musculoskeletal Disorders and Its Surgery Department, Faculty of Physical Therapy, Cairo University, Cairo, Egypt.
Roshdy Mohamed KamelBasic Sciences Department, Faculty of Physical Therapy, Benha University, Benha, Egypt.
Kamaleldin Ahmed KamalPhysical Therapy for Integumentary Department, Faculty of Physical Therapy, Benha University, Benha, 13511, Egypt.
Mahmoud ElshazlyPhysical Therapy for Surgery Department, Faculty of Physical Therapy, South Valley University, South Valley, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe objective of this research was to synthesize the evidence about the usage of pulsed electromagnetic field (PEMF) in women with breast cancer undergoing hypo-fractionated whole-breast irradiation (HFWBI) for the treatment of acute radiodermatitis.

methodsThe study included 50 patients (35-55 years) with unilateral breast cancer post-lumpectomy who received HFWBI. They were randomized into Group A (PEMF plus standard skin care) and Group B (standard skin care only). Skin reactions were assessed during PEMF therapy using sonographic skin thickness measurements and RTOG criterion.

resultsAfter radiation, skin thickness increased in both groups, peaking at 4 weeks (PEMF 2.82 mm; control 2.74 mm, p = 0.030). By 6 weeks, thickness declined in the PEMF group but remained high in controls (p < 0.001), and by 8 weeks PEMF returned near baseline (2.01 mm) while controls stayed thickened (p < 0.001). Skin reactions worsened in both groups by week 4, with more severe cases in controls (36% vs. 12%, p = 0.150). By week 6, PEMF patients mostly had mild reactions (72% Grade 0-1) compared to predominantly severe reactions in controls (84% Grade 2-3, p = 0.001). At 8 weeks, recovery was greater with PEMF, as 52% returned to Grade 0 versus only 8% in controls (p = 0.001).

conclusionResults such as these indicate that PEMF therapy accelerates recovery from radiotherapy and diminishes the intensity of acute radiodermatitis.

trial registrationTrial registration number: NCT06003764. Date of registration: 12 August 2023. Prospectively registered for prospectively registered trials.

Indexed as

Breast NeoplasmsMagnetic Field TherapyRadiodermatitisAcute DiseaseAdultFemaleHumansMastectomy, SegmentalMiddle AgedHypo-fractionated whole breast irradiationPulsed electromagnetic fieldRadiation Therapy Oncology GroupSonography

Identifiers

PMID41642361
PMCPMC12876086

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.