Evidence map›Paper›PMID 41642345›Full record

ArticleZeitschrift fur Rheumatologie2026

[Consequences of late access to specialist care-effect on medication costs in rheumatoid arthritis].

Luisa V Licker, Nicolas Pardey, Kristine Kreis, Jona T Stahmeyer, Silke Zinke, Dirk Meyer-Olson, Torsten Witte, Kirsten Hoeper, Jan Zeidler

Abstract readEnglish Abstract
In one paragraph

Article in Zeitschrift fur Rheumatologie, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Luisa V LickerCenter for Health Economics Research Hannover (CHERH), Leibniz Universität Hannover, Königsworther Platz 1, 30617, Hannover, Deutschland. luisa.licker@ihe.uni-hannover.de.ORCID http://orcid.org/0009-0006-9003-2656
Nicolas PardeyCenter for Health Economics Research Hannover (CHERH), Leibniz Universität Hannover, Königsworther Platz 1, 30617, Hannover, Deutschland.
Kristine KreisKlinik für Rheumatologie und klinische Immunologie, Medizinische Hochschule Hannover, Hannover, Deutschland.ORCID http://orcid.org/0000-0002-3914-0575
Jona T StahmeyerStabsbereich Versorgungsforschung, AOK Niedersachsen, Die Gesundheitskasse, Hannover, Deutschland.
Silke ZinkeRheumatologische Schwerpunktpraxis Berlin, Berlin, Deutschland.
Dirk Meyer-OlsonKlinik für Rheumatologie und klinische Immunologie, Medizinische Hochschule Hannover, Hannover, Deutschland.
Torsten WitteKlinik für Rheumatologie und klinische Immunologie, Medizinische Hochschule Hannover, Hannover, Deutschland.ORCID http://orcid.org/0000-0003-4531-0267
Kirsten HoeperKlinik für Rheumatologie und klinische Immunologie, Medizinische Hochschule Hannover, Hannover, Deutschland.ORCID http://orcid.org/0000-0002-4327-9836
Jan ZeidlerCenter for Health Economics Research Hannover (CHERH), Leibniz Universität Hannover, Königsworther Platz 1, 30617, Hannover, Deutschland.ORCID http://orcid.org/0000-0002-0104-2267

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundInsufficient access to specialist rheumatology services in Germany results in prolonged waiting times and delayed diagnostic confirmation, which impedes timely and effective initiation of therapy.

objectivesThis study examines the impact of early versus delayed access to specialist care on medication prescribing patterns and associated costs. MATERIALS AND

methodsA cost analysis was conducted within the Deliver-Care study using health insurance claims data from 2015-2020. Patients with a confirmed rheumatoid arthritis diagnosis (ICD-10 M05/M06) were stratified by the timing of their initial specialist consultation: early access (within the diagnosis quarter, Q1) versus late access (Q2-Q4). Medication costs were compared across these groups.

resultsMore than half (57.4%) of M05 patients and about one quarter (24.4%) of M06 patients had no access to a specialist during the first year after the initial suspected diagnosis. Among patients who did have specialist contact (n = 3781), 82.7% obtained early specialist access. Patients with delayed specialist access incurred higher medication costs (€ 4343 in Q4 vs. € 1763 in Q1; p < 0.0001). A sensitivity analysis showed that patients with delayed specialist access were switched to high-cost medications earlier than those with early access.

conclusionEarly specialist access is associated with reduced biologic prescribing and lower medication costs. These findings highlight that timely diagnosis and treatment not only lessen patient disease burden but also generate substantial cost savings in the management of rheumatoid arthritis.

Indexed as

Antirheumatic AgentsArthritis, RheumatoidDrug CostsHealth Services AccessibilityAgedFemaleGermanyHumansMaleMiddle AgedReferral and ConsultationRheumatologySpecializationTreatment DelayAntirheumatic AgentsClaims dataCost analysisDMARD therapyEarly specialist access

Identifiers

PMID41642345
PMCPMC13124890

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.