Evidence map›Paper›PMID 41642342›Full record

ArticleAnalytical and bioanalytical chemistry2026

Supramolecular solvents based on deep eutectic solvents and hexafluorobutanol for the extraction of aristolochic acids from natural plants.

Wenxu Hu, Dandan Ge, Feie Fu, Lin Yuan, Chunyan Yang, Zhehui Weng, Yao Huang

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Article in Analytical and bioanalytical chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Wenxu HuSchool of Chemical Engineering, Yunnan Open University, Kunming, 650504, Yunnan, China.
Dandan GeSchool of Chemical Engineering, Yunnan Open University, Kunming, 650504, Yunnan, China. dandangeiris@163.com.ORCID http://orcid.org/0000-0002-5827-7454
Feie FuSchool of Chemical Engineering, Yunnan Open University, Kunming, 650504, Yunnan, China.
Lin YuanSchool of Chemistry and Chemical Engineering, Kunming University, Kunming, 650214, Yunnan, China.
Chunyan YangSchool of Chemical Engineering, Yunnan Open University, Kunming, 650504, Yunnan, China.
Zhehui WengSchool of Chemical Engineering, Yunnan Open University, Kunming, 650504, Yunnan, China.
Yao HuangSchool of Chemical Engineering, Yunnan Open University, Kunming, 650504, Yunnan, China.

Funding

Education Department Project of Yunnan Province 2025Y1060Special Basic Cooperative Research Programs of Yunnan Provincial Undergraduate Universities' Association 202101BA070001-051Special Basic Cooperative Research Programs of Yunnan Provincial Undergraduate Universities' Association 202301BA070001-020
6 · The paper itself

Abstract

In this study, a new liquid phase microextraction method was developed by combining micelle-mediated extraction of aristolochic acids (AAs) in traditional Chinese medicines with polyfluorinated alcohol solutions, and subsequent preconcentration via deep eutectic solvent (DES)-induced supramolecular solvent (SUPRAS) formation. The preparation of SUPRASs with polyfluorinated alcohols functioning as amphiphiles and the DESs acting as coacervation agents is demonstrated for the first time. Different polyfluorinated alcohols and DESs were examined for the extraction and preconcentration of AAs. The SUPRAS prepared from hexafluorobutanol (HFB) and a DES based on (1) octanol:(2) fenchyl alcohol achieved the highest extraction efficiency. Compared to traditionally used surfactants such as octanol, octanoic acid, and octylamine, HFB exhibited better extraction efficiency of AAs. The optimized method provided good linearity in the range of 0.14-500 µg g

Indexed as

Aristolochic AcidsDeep Eutectic SolventsLiquid Phase MicroextractionFluorocarbonsHydrocarbons, FluorinatedMicellesPropanolsSolventsAristolochic AcidsDeep Eutectic SolventsFluorocarbonshexafluoroisopropanolHydrocarbons, FluorinatedMicellesPropanolsSolventsAristolochic acidsDeep eutectic solventHexafluorobutanolHigh-performance liquid chromatographySupramolecular solvent

Identifiers

PMID41642342

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.