Evidence map›Paper›PMID 41642298›Full record

ArticleEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2026

Disc-level predictors of indirect decompression of posterior cord compression by the ligamentum flavum following anterior cervical discectomy and fusion.

Hiroaki Kimura, Juichi Miura, Atsushi Tanaka, Yushi Sakamoto, Taiichi Matsumoto

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Article in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

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5 authors.

Hiroaki KimuraDepartment of Orthopedic Surgery, Hyogo Prefectural Amagasaki General Medical Center, Amagasaki, Hyogo, Japan. hkimura613@gmail.com.
Juichi MiuraDepartment of Orthopedic Surgery, Hyogo Prefectural Amagasaki General Medical Center, Amagasaki, Hyogo, Japan.
Atsushi TanakaDepartment of Orthopedic Surgery, Hyogo Prefectural Amagasaki General Medical Center, Amagasaki, Hyogo, Japan.
Yushi SakamotoDepartment of Orthopedic Surgery, Hyogo Prefectural Amagasaki General Medical Center, Amagasaki, Hyogo, Japan.
Taiichi MatsumotoDepartment of Orthopedic Surgery, Hyogo Prefectural Amagasaki General Medical Center, Amagasaki, Hyogo, Japan.

Funding

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6 · The paper itself

Abstract

purposeAnterior cervical discectomy and fusion (ACDF) is commonly performed to treat cervical myelopathy. However, its effectiveness in decompressing posterior structures like hypertrophied ligamentum flavum, remains unclear. This study aimed to identify disc-level factors that predict radiographic improvement of posterior cord compression caused by ligamentum flavum (CCLF) after ACDF.

methodsWe retrospectively analyzed 75 cervical disc levels from 43 patients who underwent ACDF for degenerative cervical disease with preoperative CCLF on MRI. Postoperative CCLF changes were evaluated, and discs were divided into improved and unimproved groups. Preoperative disc angle, segmental lordosis, disc height, preoperative disc range of motion, cage-to-disc ratio, Hounsfield units (HU) values, and facet joint degeneration were compared. Multivariate logistic regression was used to identify independent predictors of failure to improve CCLF.

resultsPostoperative improvement in the CCLF was observed in 59 of 75 disc levels (79%). The unimproved group showed significantly larger preoperative disc angles (5.1° vs. 2.3°, p = 0.003) and higher HU values (368 vs. 326, p = 0.04). In addition, advanced facet osteoarthritis was significantly more frequent in the unimproved group (P = 0.027). Multivariate analysis demonstrated that greater preoperative disc angle (odds ratio [OR]: 1.21, 95% confidence interval [CI]: 1.01-1.45, p = 0.041), higher HU values (OR: 1.007, 95% CI: 1-1.015, p = 0.048) and advanced facet degeneration (OR = 8.92, 95% CI: 1.01-78.6, p = 0.049) were independently associated with failure to improve CCLF.

conclusionIndirect decompression via ACDF may be less effective in segments with greater disc angles, higher bone densities, or advanced facet degeneration. These findings highlight the importance of preoperative disc-level assessment in surgical planning.

Indexed as

Cervical VertebraeDecompression, SurgicalDiskectomyIntervertebral DiscLigamentum FlavumSpinal Cord CompressionSpinal FusionAdultAgedFemaleHumansMaleMiddle AgedRetrospective StudiesTreatment Outcomeanterior cervical discetomy and fusion (ACDF), indirect decompression, cervical myelopathy, disc angle, cervical spine surgery, ligamentum flavum hypertrophy, Housfield unit (HU), facet osteoarthritis

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.