ArticleAbdominal radiology (New York)2026
Integrating shear wave elastography and clinical characteristics for noninvasive diagnosis of IgA nephropathy.
Article in Abdominal radiology (New York), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed.
- IgA Nephropathy: Mechanisms, Risk Stratification, and Precision Therapy.Diagnostics (Basel, Switzerland) · 2026Review
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Authors and funding
7 authors.
Funding
Abstract
purposeTo develop and validate a diagnostic model for IgA nephropathy (IgAN) based on Shear Wave Elastography (SWE) and clinical characteristics.
methodsThis study enrolled 270 patients with primary glomerulonephritis who underwent renal biopsy at the Fifth Affiliated Hospital of Sun Yat-sen University between November 2019 and November 2023. Among the study cohort, there were 152 IgAN patients. Biochemical and ultrasound examinations including SWE examination were performed within one week prior to biopsy. Univariate and multivariate analyses were used to determine the independent predictors of IgAN.
resultsMultivariate logistic regression identified age, estimated glomerular filtration rate (eGFR), serum albumin, 24-hour urinary protein, and mean SWE value as independent predictors of IgAN. In the training cohort, our model achieved an area under the receiver operating characteristic curve (AUC) of 0.921 (95% CI: 0.879-0.962), and 0.806 (95% CI: 0.707-0.905) in the validation cohort. A nomogram integrating the aforementioned independent risk factors was constructed, facilitating practical use for clinicians.
conclusionThe integrated clinical and SWE model demonstrates good diagnostic performance for IgAN. It is simple to implement and holds significant clinical value as a potential non-invasive diagnostic tool.
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