Evidence map›Paper›PMID 41642235›Full record

ReviewAnnual review of clinical psychology2026

Affective Sensitivity to Ovarian Steroid Hormone Flux Across the Menstrual Cycle: Manifestations and Biopsychosocial Risk Factors.

Allison Stumper, Katja M Schmalenberger, Tory A Eisenlohr-Moul, Jessica R Peters

Abstract readReview
In one paragraph

Review in Annual review of clinical psychology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Allison StumperBradley Hospital, East Providence, Rhode Island, USA.
Katja M SchmalenbergerDepartment of Psychiatry, University of Illinois Chicago, Chicago, Illinois, USA.
Tory A Eisenlohr-MoulDepartment of Psychiatry, University of Illinois Chicago, Chicago, Illinois, USA.
Jessica R PetersDepartment of Psychiatry and Human Behavior, The Warren Alpert Medical School of Brown University, Providence, Rhode Island, USA; email: Allison_stumper@brown.edu.

Funding

Ovarian Steroid Effects on Mood and Sleep Across the Adolescent Menstrual CycleK23MH136325 · NIMH · EMMA PENDLETON BRADLEY HOSPITAL · PI Allison Stumper · 2024 to 2026
$590k
NIMH NIH HHS K23 MH136325
6 · The paper itself

Abstract

Hormone sensitivity is a heterogeneous phenomenon involving multiple dimensions of sensitivity to estrogen and progesterone fluctuations across the menstrual cycle. While the majority of menstruating individuals do not experience any significant impact from these hormone changes on mood or behavior, rates of hormone sensitivity in clinical populations, particularly affective disorders, are substantially elevated, suggesting potential shared psychosocial or physiological mechanisms or moderators of risk. In this review, we provide an overview of menstrually related mood disorders and dimensions of hormone sensitivity across the cycle contributing to these presentations. We discuss how hormone sensitivity during the menstrual cycle corresponds with affective problems during other reproductive life events (puberty, perimenopause, pregnancy/postpartum) and review the evidence for environmental, neurobiological, and cognitive/affective factors associated with hormone sensitivity. Methodological considerations and directions for further research are highlighted throughout.

Indexed as

EstrogensMenstrual CycleMood DisordersPremenstrual Dysphoric DisorderProgesteroneFemaleHumansRisk FactorsEstrogensProgesteroneaffective disordershormone sensitivitymenstrual cyclePMDDpremenstrual dysphoric disorderreproductive lifespan

Identifiers

PMID41642235
PMCPMC13213724

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.