Evidence map›Paper›PMID 41642226›Full record

ArticleeLife2026

ZFT is the major iron and zinc transporter in

Dana Aghabi, Cecilia Gallego Rubio, Miguel Cortijo Martinez, Augustin Pouzache, Erin J Gibson, Lucas Pagura, Stephen J Fairweather, Giel G van Dooren, Clare R Harding

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in eLife, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Dana AghabiCentre for Parasitology, School of Infection and Immunity, University of Glasgow, Glasgow, United Kingdom.ORCID https://orcid.org/0000-0002-7827-5296
Cecilia Gallego RubioCentre for Parasitology, School of Infection and Immunity, University of Glasgow, Glasgow, United Kingdom.
Miguel Cortijo MartinezCentre for Parasitology, School of Infection and Immunity, University of Glasgow, Glasgow, United Kingdom.
Augustin PouzacheCentre for Parasitology, School of Infection and Immunity, University of Glasgow, Glasgow, United Kingdom.
Erin J GibsonCentre for Parasitology, School of Infection and Immunity, University of Glasgow, Glasgow, United Kingdom.ORCID https://orcid.org/0009-0009-7648-1318
Lucas PaguraCentre for Parasitology, School of Infection and Immunity, University of Glasgow, Glasgow, United Kingdom.ORCID https://orcid.org/0000-0003-1061-6311
Stephen J FairweatherResearch School of Biology, Australian National University, Canberra, Australia.ORCID https://orcid.org/0000-0003-1530-7876
Giel G van DoorenResearch School of Biology, Australian National University, Canberra, Australia.ORCID https://orcid.org/0000-0003-2455-9821
Clare R HardingCentre for Parasitology, School of Infection and Immunity, University of Glasgow, Glasgow, United Kingdom.ORCID https://orcid.org/0000-0002-8428-0374

Funding

Australian Research Council DP230100853Biotechnology and Biological Sciences Research Council BB/W014947/1Biotechnology and Biological Sciences Research Council BB/X010902/1Wellcome 10.35802/213455Wellcome 10.35802/218518Wellcome Trust
6 · The paper itself

Abstract

Transition metals, such as iron and zinc, are indispensable trace elements for eukaryotic life, acting as co-factors in essential processes ranging from metabolism to DNA replication. These metals can be transported into cells by an evolutionary-conserved family of metal transporters; however, how the ubiquitous mammalian parasite

Indexed as

Cation Transport ProteinsIronProtozoan ProteinsToxoplasmaZincAnimalsBiological TransportCell LineCell MembraneGene Knockdown TechniquesHumansMitochondriaRecombinant ProteinsXenopusCation Transport ProteinsIronProtozoan ProteinsRecombinant ProteinsZincinfectious diseaseironmetabolismmicrobiologyToxoplasma gondiitransporterzinc

Identifiers

PMID41642226
PMCPMC12875612

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.