Evidence map›Paper›PMID 41642162›Full record

ArticleJACC. Case reports2026

ICE-Guided Percutaneous Thrombectomy of Thrombus-in-Transit With Impending Paradoxical Embolism Through PFO and Pulmonary Embolism.

Timothy Ho Him Kam, Cheuk Yin Lai, Leo Kar Lok Lai, Ling Na Wong, Kent Chak Yu So, Bryan Ping Yen Yan, Alex Pui Wai Lee, Guangming Tan

Abstract readCase Reports
In one paragraph

Article in JACC. Case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Timothy Ho Him KamDivision of Cardiology, Department of Medicine & Therapeutics, Prince of Wales Hospital, Shatin, Hong Kong, China.
Cheuk Yin LaiDivision of Cardiology, Department of Medicine & Therapeutics, Prince of Wales Hospital, Shatin, Hong Kong, China.
Leo Kar Lok LaiDivision of Cardiology, Department of Medicine & Therapeutics, Prince of Wales Hospital, Shatin, Hong Kong, China.
Ling Na WongDivision of Cardiology, Department of Medicine & Therapeutics, Prince of Wales Hospital, Shatin, Hong Kong, China.
Kent Chak Yu SoDivision of Cardiology, Department of Medicine & Therapeutics, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, Hong Kong, China.
Bryan Ping Yen YanDivision of Cardiology, Department of Medicine & Therapeutics, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, Hong Kong, China.
Alex Pui Wai LeeLaboratory of Cardiovascular Imaging and 3D Printing, Li Ka Shing Institute of Health Sciences, Shatin, Hong Kong, China.
Guangming TanFaculty of Medicine, Li Ka Shing Institute of Health Sciences, Shatin, Hong Kong, China. Electronic address: gtan@cuhk.edu.hk.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveImpending paradoxical embolism (IPE), defined as thrombus entrapped across a patent foramen ovale, is rare in acute pulmonary embolism (PE) and is associated with high mortality. We present to our knowledge the first successful intracardiac echocardiography (ICE)-guided mechanical thrombectomy for simultaneous treatment of right ventricular thrombus-in-transit (TIT), IPE, and high-risk PE. KEY STEPS: ICE was used to locate the mobile TIT straddling the patent foramen ovale. For embolic protection, a Sentinel cerebral protection system was deployed via the right radial artery, while a blocking balloon positioned in the left subclavian artery. A 24-F femoral venous access enabled advancement of the AlphaVac F18 POTENTIAL PITFALLS: Percutaneous thrombectomy is feasible for patients unsuitable for surgery or thrombolysis but carries a risk of paradoxical embolization. Embolic protection is therefore essential. TAKE-HOME MESSAGE: ICE-guided AlphaVac thrombectomy of TIT, IPE, and PE is feasible in high-risk patients.

Indexed as

impending paradoxical embolismintracardiac echocardiogrampatent foramen ovalepercutaneous thrombectomypulmonary embolismthrombus-in-transit

Identifiers

PMID41642162
PMCPMC13008511

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.