Evidence map›Paper›PMID 41641899›Full record

ArticleHuman brain mapping2026

segcsvd

Erin Gibson, Joel Ramirez, Lauren Abby Woods, Stephanie Berberian, Julie Ottoy, Christopher J M Scott, Vanessa Yhap, Fuqiang Gao, Roberto Duarte Coello, Maria Valdes Hernandez and 15 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Human brain mapping, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Observational
  2. G-ALPS: An index for evaluating cognitive decline and aging using diffusion tensor imaging.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Article
  3. segcsvdHuman brain mapping · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors.

Erin GibsonSB Centre for Brain Resilience & Recovery, Hurvitz Brain Sciences Program, Sunnybrook Research Institute, University of Toronto, Toronto, Ontario, Canada.ORCID https://orcid.org/0000-0001-5823-0173
Joel RamirezSB Centre for Brain Resilience & Recovery, Hurvitz Brain Sciences Program, Sunnybrook Research Institute, University of Toronto, Toronto, Ontario, Canada.
Lauren Abby WoodsSB Centre for Brain Resilience & Recovery, Hurvitz Brain Sciences Program, Sunnybrook Research Institute, University of Toronto, Toronto, Ontario, Canada.
Stephanie BerberianSB Centre for Brain Resilience & Recovery, Hurvitz Brain Sciences Program, Sunnybrook Research Institute, University of Toronto, Toronto, Ontario, Canada.
Julie OttoySB Centre for Brain Resilience & Recovery, Hurvitz Brain Sciences Program, Sunnybrook Research Institute, University of Toronto, Toronto, Ontario, Canada.
Christopher J M ScottSB Centre for Brain Resilience & Recovery, Hurvitz Brain Sciences Program, Sunnybrook Research Institute, University of Toronto, Toronto, Ontario, Canada.
Vanessa YhapSB Centre for Brain Resilience & Recovery, Hurvitz Brain Sciences Program, Sunnybrook Research Institute, University of Toronto, Toronto, Ontario, Canada.
Fuqiang GaoSB Centre for Brain Resilience & Recovery, Hurvitz Brain Sciences Program, Sunnybrook Research Institute, University of Toronto, Toronto, Ontario, Canada.
Roberto Duarte CoelloUniversity of Edinburgh, Edinburgh, UK.
Maria Valdes HernandezUniversity of Edinburgh, Edinburgh, UK.ORCID https://orcid.org/0000-0003-2771-6546
Anthony E LangUniversity Health Network's Krembil Brain Institute, Edmond J Safra Program in Parkinson's Disease and the Rossy PSP Centre, Toronto Western Hospital, Toronto, Ontario, Canada.
Carmela M TartagliaUniversity Health Network's Krembil Brain Institute, Edmond J Safra Program in Parkinson's Disease and the Rossy PSP Centre, Toronto Western Hospital, Toronto, Ontario, Canada.
Sanjeev KumarAdult Neurodevelopment and Geriatric Psychiatry, Centre for Addiction and Mental Health, Toronto, Ontario, Canada.
Malcolm A BinnsRotman Research Institute, Baycrest Health Sciences, Toronto, Ontario, Canada.
Robert BarthaRobarts Research Institute, Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada.
Sean SymonsDepartment of Medical Imaging, University of Toronto, Toronto, Ontario, Canada.
Richard H SwartzSB Centre for Brain Resilience & Recovery, Hurvitz Brain Sciences Program, Sunnybrook Research Institute, University of Toronto, Toronto, Ontario, Canada.
Mario MasellisSB Centre for Brain Resilience & Recovery, Hurvitz Brain Sciences Program, Sunnybrook Research Institute, University of Toronto, Toronto, Ontario, Canada.
Navneet SinghDepartment of Medical Imaging, University of Toronto, Toronto, Ontario, Canada.ORCID https://orcid.org/0000-0001-9719-2042
Bradley J MacIntoshSB Centre for Brain Resilience & Recovery, Hurvitz Brain Sciences Program, Sunnybrook Research Institute, University of Toronto, Toronto, Ontario, Canada.ORCID https://orcid.org/0000-0001-7300-2355
Joanna M WardlawUniversity of Edinburgh, Edinburgh, UK.
Sandra E BlackSB Centre for Brain Resilience & Recovery, Hurvitz Brain Sciences Program, Sunnybrook Research Institute, University of Toronto, Toronto, Ontario, Canada.
ONDRI Investigators, ADNI, CAHHM Investigators, CAIN Investigators, colleagues from the Foundation Leducq Transatlantic Network of Excellence
Andrew S P LimSB Centre for Brain Resilience & Recovery, Hurvitz Brain Sciences Program, Sunnybrook Research Institute, University of Toronto, Toronto, Ontario, Canada.
Maged GoubranSB Centre for Brain Resilience & Recovery, Hurvitz Brain Sciences Program, Sunnybrook Research Institute, University of Toronto, Toronto, Ontario, Canada.ORCID https://orcid.org/0000-0001-5880-0818

Funding

CIHR PJT173387CIHR PJT190220
6 · The paper itself

Abstract

Enlarged perivascular spaces (PVS) are imaging markers of cerebral small vessel disease (CSVD) that are associated with age, disease phenotypes, and overall health. Quantification of PVS is challenging but necessary to expand an understanding of their role in cerebrovascular pathology. Accurate and automated segmentation of PVS on T

Indexed as

Cerebral Small Vessel DiseasesConvolutional Neural NetworksGlymphatic SystemImage Interpretation, Computer-AssistedImage Processing, Computer-AssistedMagnetic Resonance ImagingNeuroimagingHumans

Identifiers

PMID41641899
PMCPMC12874998

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.