Evidence map›Paper›PMID 41641892›Full record

ArticleStatistics in medicine2026

Nothing to See Here? A Non-Inferiority Approach to Parallel Trends.

Alyssa Bilinski, Laura A Hatfield

Abstract read
In one paragraph

Article in Statistics in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Alyssa BilinskiDepartments of Health Services, Policy, and Practice & Biostatistics, Brown School of Public Health, Providence, Rhode Island, USA.ORCID https://orcid.org/0000-0001-9108-6660
Laura A HatfieldStatistics and Data Science Department, NORC, Chicago, Illinois, USA.ORCID https://orcid.org/0000-0003-0366-3929

Funding

Observational causal inference with infectious disease outcomesR35GM155224 · NIGMS · BROWN UNIVERSITY · PI Alyssa Bilinski · 2024 to 2026
$1.1M
AHRQ HHS R01HS028985, LHNIGMS NIH HHS 1R35GM155224, ABNIGMS NIH HHS R35 GM155224
6 · The paper itself

Abstract

Difference-in-differences is a popular method for observational health policy evaluation. It relies on a causal assumption that in the absence of intervention, treatment groups' outcomes would have evolved in parallel to those of comparison groups. Researchers frequently look for parallel trends in the pre-intervention period to bolster confidence in this assumption. The popular "parallel trends test" evaluates a null hypothesis of parallel trends and, failing to find evidence against the null, concludes that the assumption holds. This tightly controls the probability of falsely concluding that trends are not parallel, but may have low power to detect non-parallel trends. When used as a screening step, it can also introduce bias in treatment effect estimates. We propose a non-inferiority/equivalence approach that tightly controls the probability of missing large violations of parallel trends, measured on the scale of the treatment effect. Our framework nests several common use cases, including linear trend tests and event studies. We show that our approach may induce no or minimal bias when used as a screening step under commonly assumed error structures and, absent violations, can offer a higher-power alternative to testing treatment effects in more flexible models. We illustrate our ideas by reconsidering a study of the impact of the Affordable Care Act's dependent coverage provision.

Indexed as

Data Interpretation, StatisticalHealth PolicyBiasComputer SimulationModels, Statisticalcausal inferencecontrolled pre/post designsequivalence testslongitudinal dataquasi‐experimental designssensitivity analysesstatistical power

Identifiers

PMID41641892
PMCPMC13126610

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.