Evidence map›Paper›PMID 41641846›Full record

Trial reportClinical pharmacology in drug development2026

A comparative pharmacokinetic evaluation of two aqueous progesterone 25 mg injections in healthy postmenopausal women under fasting conditions: An open-label, balanced, randomized, two-treatment, two-period, two-sequence, single-dose, crossover bioequivalence study.

Noopur Vyas, Amaresh Chakra, Prashant Sarode, Shruti Dharmadhikari, Gaurav Puppalwar, Chintan Khandhedia, Amey Mane, Alpesh Goyani, Ajay Jaysingh Khopade

Abstract readRandomized Controlled TrialComparative Study
In one paragraph

Trial report in Clinical pharmacology in drug development, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Noopur VyasSun Pharma Laboratories Ltd., Mumbai, India.
Amaresh ChakraSun Pharmaceutical Industries Ltd., Vadodara, India.
Prashant SarodeSun Pharmaceutical Industries Ltd., Vadodara, India.
Shruti DharmadhikariSun Pharma Laboratories Ltd., Mumbai, India.
Gaurav PuppalwarSun Pharma Laboratories Ltd., Mumbai, India.
Chintan KhandhediaSun Pharma Laboratories Ltd., Mumbai, India.
Amey ManeSun Pharma Laboratories Ltd., Mumbai, India.
Alpesh GoyaniSun Pharmaceutical Industries Ltd., Vadodara, India.
Ajay Jaysingh KhopadeSun Pharmaceutical Industries Ltd., Vadodara, India.

Funding

Sun Pharma Laboratories Limited, India
6 · The paper itself

Abstract

The growing demand for assisted reproductive technology (ART) has increased the need for effective luteal phase support. Progesterone, essential for maintaining early pregnancy, is a critical component of ART. This open-label, balanced, randomized, two-treatment, crossover, single-dose study compared the bioequivalence of aqueous progesterone 25 mg injection (AqSusten

Indexed as

FastingPostmenopauseProgesteroneArea Under CurveCross-Over StudiesFemaleHealthy VolunteersHumansMiddle AgedTherapeutic EquivalencyProgesteroneaqueous progesteroneassisted reproductive technologybioequivalenceluteal phase supportpharmacokinetics

Identifiers

PMID41641846
PMCPMC12875009

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.