Evidence map›Paper›PMID 41641600›Full record

ArticleTransfusion2026

The different barriers to donating plasma in plasma donors, whole blood donors, and non-donors in the United Kingdom.

Roshan Desai, Richard Mills, Barbara Masser, Tiffany Jones, Tamara Edwards, Susan R Brailsford, Niall O'Hagan, Charlotte Washington, Eamonn Ferguson

Abstract read
In one paragraph

Article in Transfusion, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Roshan DesaiSchool of Psychology, University of Nottingham, Nottingham, UK.ORCID https://orcid.org/0009-0005-8870-4989
Richard MillsSchool of Psychology, University of Nottingham, Nottingham, UK.ORCID https://orcid.org/0000-0002-1161-5815
Barbara MasserNational Institute for Health and Care Research Blood and Transplant Research Unit in Donor Health and Behaviour, University of Cambridge, Cambridge, UK.ORCID https://orcid.org/0000-0001-9385-6497
Tiffany JonesNHSBT, Bristol, UK.
Tamara EdwardsNHSBT, Bristol, UK.
Susan R BrailsfordSchool of Psychology, University of Nottingham, Nottingham, UK.ORCID https://orcid.org/0000-0003-2856-0387
Niall O'HaganSchool of Psychology, University of Nottingham, Nottingham, UK.ORCID https://orcid.org/0009-0007-9796-3215
Charlotte WashingtonNHSBT, Bristol, UK.
Eamonn FergusonSchool of Psychology, University of Nottingham, Nottingham, UK.ORCID https://orcid.org/0000-0002-7678-1451

Funding

NHS Blood and Transplant 136TRAN24
6 · The paper itself

Abstract

backgroundPlasma donation is critical for the production of plasma-derived medicinal products, yet donor recruitment and retention remains challenging within a volunteer system. This paper explores deterrents to plasma donation among current plasma donors, whole-blood donors, lapsed whole-blood donors, and non-donors in the United Kingdom, and self-reported post-donation symptoms in plasma donors. STUDY DESIGN AND

methodsAn online survey of the UK general public (current and lapsed blood donors, and non-donors: n = 2861) and English current plasma donors (n = 448), and one-to-one interviews (n = 25) with plasma donors were conducted. Participants identified deterrents to plasma donation, and plasma donors described post-donation symptoms.

resultsPlasma donors reported distinct deterrents around time constraints and ineligibility. There were differences by donor status. Blood, plasma, and non-donors all report pain, lack of travel compensation, involvement of private companies and incentives as concerns. Lack of awareness was salient for non-donors and blood donors, while non-donors had concerns about neurodiversity and donors about incentives to change. Being deferred on the day, described as an embarrassing "walk of shame," was a unique deterrent to plasma donors. 11.8% (53/488) of plasma donors reported symptoms of feeling ill after donation. Of these, 73% (n = 38) occurred and were managed in center (e.g., feeling faint, bruising) and 25% (n = 13) outside of the center (e.g., feeling faint) and managed by the donor (2% other). DISCUSSION: Different profiles of deterrents were observed for plasma donors compared to whole blood and non-donors. Recommendations for the recruitment and retention of plasma donors in England are discussed.

Indexed as

Blood DonationBlood DonorsPlasmaAdolescentAdultFemaleHumansMaleMiddle AgedSurveys and QuestionnairesUnited KingdomYoung Adult

Identifiers

PMID41641600
PMCPMC12983118

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.