ArticleRespirology case reports2026
Autoimmune/Inflammatory Syndrome Induced by Adjuvants With Sarcoid-Like Pulmonary Lesions Triggered by Silicone Implant Rupture and Improved After Explantation.
Article in Respirology case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Silicone implants can trigger adjuvant-induced autoimmune/inflammatory syndrome (ASIA). We present a 53-year-old woman who had undergone bilateral intramuscular silicone breast implantation at X-24 years. Following implant rupture at X year, she developed cough, fatigue, and arthralgia, accompanied by worsening sarcoid-like pulmonary lesions. After implant removal, her clinical symptoms and radiological findings improved. Histopathological examination findings identified foreign-body granulomas, fulfilling diagnostic criteria for ASIA. This case suggests that silicone leakage after implant rupture, rather than the duration of exposure, is a critical factor in disease development and progression. The sarcoid-like pulmonary lesions in this case may represent a sarcoid-like granulomatous reaction triggered by silicone exposure in the setting of ASIA, rather than true systemic sarcoidosis. Early implant removal appears beneficial for both the diagnosis and treatment of ASIA.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.