Evidence map›Paper›PMID 41641377›Full record

ArticleRespirology case reports2026

Rheumatoid Arthritis Preceded by Interstitial Lung Disease Controlled by Long-Term Treatment With the Janus Kinase 1-Selective Inhibitor, Filgotinib: A Case Report.

Takeo Sato, Shoko Nakazawa, Shotaro Yamamoto, Katsuya Nagatani, Kojiro Sato

Abstract read
In one paragraph

Article in Respirology case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Takeo SatoDivision of Rheumatology and Clinical Immunology, Department of Medicine Jichi Medical University Shimotsuke Tochigi Japan.ORCID https://orcid.org/0009-0002-3354-6571
Shoko NakazawaDivision of Pulmonary Disease, Department of Medicine Shin-Oyama City Hospital Oyama Tochigi Japan.
Shotaro YamamotoDivision of Rheumatology and Clinical Immunology, Department of Medicine Jichi Medical University Shimotsuke Tochigi Japan.
Katsuya NagataniDivision of Rheumatology and Clinical Immunology, Department of Medicine Jichi Medical University Shimotsuke Tochigi Japan.
Kojiro SatoDivision of Rheumatology and Clinical Immunology, Department of Medicine Jichi Medical University Shimotsuke Tochigi Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We present a case of active interstitial lung disease (ILD) preceding the onset of rheumatoid arthritis (RA). A 68-year-old man had dyspnea, decreased forced vital capacity, and elevated Krebs von den Lungen-6 levels. Non-specific interstitial pneumonia-like patterns, including ground-glass opacities, fibrosis, and subpleural spared area, were observed on computed tomography. Both rheumatoid factor and anti-cyclic citrullinated peptide antibody were positive; however, he had no clinical evidence of arthritis. Two years later, he developed arthritis, which was diagnosed as RA with high disease activity. He was started on salazosulfapyridine, which had no effect on the arthritis. Filgotinib, a selective Janus kinase (JAK) 1 inhibitor, was added for arthritis treatment; thereafter, the ILD improved alongside the arthritis. He maintained remission for 4 years with no exacerbation, flare, or adverse events. JAK1 inhibitor may be safe and beneficial in the long-term control and treatment of arthritis and ILD.

Indexed as

filgotinibground‐glass opacitiesJanus kinase 1non‐specific interstitial pneumoniarheumatoid arthritis‐associated interstitial lung disease

Identifiers

PMID41641377
PMCPMC12863997

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.