ArticleParkinson's disease2026
Temporal Discrimination and Proprioceptive Impairment in Parkinson's Disease: Evidence for Distinct Sensory Dysfunction Mechanisms.
Article in Parkinson's disease, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Turns and Turn-Related Falls: Stepping on a Rotating Platform as a Potential Approach to Foster Adapted Muscular and Neural Plasticity in Fragile Persons and Patients with Motor Impairment.Brain sciences · 2026Article
- Temporal Discrimination and Proprioceptive Impairment in Parkinson's Disease: Evidence for Distinct Sensory Dysfunction Mechanisms.Parkinson's disease · 2026Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Parkinson's disease (PD) is characterized by motor symptoms but also includes nonmotor impairments such as sensory disturbances. Temporal discrimination (TD) deficits have been repeatedly demonstrated, while proprioceptive dysfunction is also common in PD. The exact significance of these alterations, and whether they represent related aspects of a common pathophysiological process, remains elusive. Methods: We investigated somatosensory and kinesthetic TD as well as proprioceptive accuracy in 20 PD patients and compared 20 age- and sex-matched healthy controls (HCs). Somatosensory TD threshold (STDT) was assessed using paired cutaneous electrical stimuli and TD motor thresholds (TDMTs) by electrically induced wrist flexions. Proprioception was measured with two tasks requiring wrist flexion to predefined angles (LED task) or to reproduce angular ranges (ARROW task), without visual feedback. Clinical assessment comprised MDS-UPDRS III, Hoehn and Yahr stage, levodopa dosage, and disease duration. Results: PD patients exhibited significantly elevated thresholds compared to HC for both STDT (120.3 ± 42.3 ms vs. 80.8 ± 17.1 ms, Conclusions: PD patients show pronounced impairments in both TD and proprioceptive accuracy, confirming sensory processing deficits beyond motor dysfunction. The absence of correlations suggests distinct mechanisms, highlighting the need for further neurophysiological research.
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Registered trials
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