Evidence map›Paper›PMID 41641340›Full record

ArticleBJUI compass2026

Safety and efficacy of Rezūm water vapour energy therapy in BPH patients receiving antithrombotic therapy: A Japanese single-centre experience.

Takatoshi Moriwake, Yusuke Tominaga, Satoshi Katayama, Haruki Kaku, Ichiro Tsuboi, Kasumi Yoshinaga, Tomoaki Yamanoi, Tatsushi Kawada, Takuya Sadahira, Takehiro Iwata and 4 more

Abstract read
In one paragraph

Article in BJUI compass, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Takatoshi MoriwakeDepartment of Urology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences Okayama University Okayama Japan.ORCID https://orcid.org/0009-0006-0163-1906
Yusuke TominagaDepartment of Urology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences Okayama University Okayama Japan.
Satoshi KatayamaDepartment of Urology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences Okayama University Okayama Japan.
Haruki KakuDepartment of Urology Okamura Isshindo Hospital Okayama Japan.
Ichiro TsuboiDepartment of Urology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences Okayama University Okayama Japan.
Kasumi YoshinagaDepartment of Urology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences Okayama University Okayama Japan.
Tomoaki YamanoiDepartment of Urology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences Okayama University Okayama Japan.
Tatsushi KawadaDepartment of Urology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences Okayama University Okayama Japan.
Takuya SadahiraDepartment of Urology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences Okayama University Okayama Japan.
Takehiro IwataDepartment of Urology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences Okayama University Okayama Japan.
Shingo NishimuraDepartment of Urology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences Okayama University Okayama Japan.
Kensuke BekkuDepartment of Urology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences Okayama University Okayama Japan.ORCID https://orcid.org/0000-0003-0002-1592
Yasuhiro KatayamaDepartment of Urology Okamura Isshindo Hospital Okayama Japan.
Motoo ArakiDepartment of Urology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences Okayama University Okayama Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: The objective of this study is to evaluate the safety and efficacy of Rezūm water vapour energy therapy (WAVE) in Japanese patients with benign prostatic hyperplasia (BPH) continuing antithrombotic therapy and to validate the Okayama University Modified Clavien-Dindo classification (OU-mCD) for perioperative hematuria. Patients and Methods: We retrospectively analysed 80 consecutive patients who underwent WAVE from August 2023 to July 2024, including 37 (46.2%) continuing antithrombotic therapy perioperatively. Hematuria within 30 days was graded using conventional Clavien-Dindo classification and the OU-mCD, a novel classification focusing on intervention necessity. We assessed clinically significant hematuria (Grade ≥ Ib), catheter-free rate, prostate volume reduction and haemoglobin change. Results: Clinically significant hematuria occurred in 21.6% (8/37) of patients continuing antithrombotic therapy versus 4.7% (2/43) without ( Conclusion: WAVE can be safely performed with continued antithrombotic therapy. Whereas Grade ≥Ib hematuria occurred in 25% of antiplatelet/anticoagulant users (vs. 5% without), 75% had no significant bleeding, and all complications were managed conservatively without transfusion. The OU-mCD provides precise complication stratification. These findings suggest outpatient procedures may be feasible with appropriate patient selection.

Indexed as

benign prostatic hyperplasiahematuriaantithrombotic therapyJapaneseOU‐mCDwater vapour energy therapy

Identifiers

PMID41641340
PMCPMC12864163

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.