SynthesisFrontiers in neurology
Efficacy and safety of stellate ganglion block for tinnitus: a systematic review and meta-analysis.
Synthesis in Frontiers in neurology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: This systematic review and meta-analysis evaluates the effectiveness and safety of stellate ganglion block (SGB) for tinnitus. Methods: A comprehensive systematic literature search was performed across four Chinese databases include China National Knowledge Infrastructure (CNKI), Wanfang, China Science and Technology Journal Database (VIP), and SinoMed. five English databases include PubMed, Cochrane Library, Embase, Ovid, and Web of Science to identify randomized controlled trials (RCTs) investigating the use of SGB for tinnitus treatment published before November 28, 2025. Searches were conducted in both Chinese and English. Following a rigorous screening process, meta-analyses were carried out using Stata 17.0 and RevMan 5.2.1 software. The study protocol was registered on PROSPERO (CRD420251242113). Results: A total of 11 randomized controlled trials comprising 915 patients were included in this study. Meta-analysis demonstrated that SGB combined other therapy was significantly more effective than the control group in treating tinnitus, with an overall effective rate (OR = 4.53, 95% CI [3.15, 6.53], Conclusion: SGB combination therapy shows promise in managing tinnitus by improving effective rates, blood flow, THI and SAS scores. However, future large-scale, rigorous trials are essential to standardize treatment, address potential bias, and confirm long-term benefits. Systematic review registration: https://www.crd.york.ac.uk/PROSPERO, identifier CRD420251242113.
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