ArticleAACE endocrinology and diabetes
Diabetic and Nondiabetic Endocrine Emergencies: Clinical Spectrum and Outcomes From a Tertiary Care Center in North India.
Article in AACE endocrinology and diabetes. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: Endocrine emergencies, although uncommon, are potentially life-threatening and require prompt diagnosis and timely intervention. Although diabetic ketoacidosis (DKA) and hyperosmolar hyperglycemic state (HHS) are well described, data on nondiabetic endocrine emergencies remain limited, particularly from low-resource settings. This study aimed to evaluate spectrum, clinical characteristics, and outcomes of endocrine emergencies presenting to a tertiary care hospital in North India. Methods: A prospective observational study was conducted over 18 months at a tertiary care academic hospital in North India. Patients aged ≥12 years presenting to the emergency department with endocrine emergencies were included. Clinical details, biochemical parameters, and outcomes were systematically recorded and analyzed. Results: A total of 212 patients were enrolled, with an incidence of 1.82 per 1000 emergency visits annually. DKA was the most frequent diagnosis (69.3%), followed by hypercalcemia (11.3%) and hypoglycemia (7.1%). HHS accounted for 3.8% of cases and had the highest mortality (50%). All patients with thyroid storm ( Conclusion: DKA is common and treatable, whereas HHS and thyroid storm carry high mortality, warranting early recognition and aggressive management.
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