SynthesisFrontiers in medicine2025
Effect of respiratory muscle training on diaphragm function in stroke patients: a systematic review and meta-analysis.
Synthesis in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
0 citing papers in PubMed.
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Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: This meta-analysis aimed to assess the effectiveness of respiratory muscle training (RMT) in restoring diaphragm function after a stroke. Methods: We conducted a comprehensive search for studies investigating the impact of RMT on diaphragm function in post-stroke patients that were published in the China National Knowledge Infrastructure, Wanfang Data, PubMed, Embase, Cochrane Library, Web of Science, Physiotherapy Evidence Database and ClinicalTrials.gov databases between inception and April 2023. Six reviewers independently screened eligible studies, extracted data and assessed methodological quality. The results were analysed using mean differences (MDs) with 95% confidence intervals (CIs), and heterogeneity was assessed using the chi-squared test and Results: This meta-analysis included 6 studies comprising 246 patients, with methodological quality ranging from poor to excellent. We observed significant differences in diaphragm mobility on the affected side after a stroke (MD = 1.32, 95% CI: 0.96-1.67; Conclusion: Respiratory muscle training can enhance diaphragm function in post-stroke patients, encompassing improvements in diaphragm mobility, thickness and thickening fraction, particularly focusing on the affected side diaphragmatic function. Systematic review registration: Trial registration CRD42022371157, available from https://www.crd.york.ac.uk/PROSPERO/view/CRD42022371157.
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