Evidence map›Paper›PMID 41641225›Full record

ArticleComputing in cardiology2025

Predicting Ventricular Arrhythmia in Myocardial Ischemia Using Machine Learning.

Anna Busatto, Jake A Bergquist, Tolga Tasdizen, Benjamin A Steinberg, Ravi Ranjan, Rob S MacLeod

Abstract read
In one paragraph

Article in Computing in cardiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Anna BusattoScientific Computing and Imaging Institute, University of Utah, SLC, UT, USA.
Jake A BergquistScientific Computing and Imaging Institute, University of Utah, SLC, UT, USA.
Tolga TasdizenScientific Computing and Imaging Institute, University of Utah, SLC, UT, USA.
Benjamin A SteinbergDepartment of Medicine, University of Utah, SLC, UT, USA.
Ravi RanjanNora Eccles Cardiovascular Research and Training Institute, University of Utah, SLC, UT, USA.
Rob S MacLeodScientific Computing and Imaging Institute, University of Utah, SLC, UT, USA.

Funding

TRD - VisualizationP41GM103545 · NIGMS · UNIVERSITY OF UTAH · PI JOHNSON, CHRISTOPHER R., MACLEOD, ROB S. · 2012 to 2019
$9.7M
Center for Integrative Biomedical Computing Legacy TransitionR24GM136986 · NIGMS · UNIVERSITY OF UTAH · PI JOHNSON, CHRISTOPHER R., MACLEOD, ROB S. · 2020 to 2022
$1.6M
Integration of Uncertainty Quantification with SCIRun Bioelectric Field Simulation PipelineU24EB029012 · NIBIB · UNIVERSITY OF UTAH · PI MACLEOD, ROB S. · 2019 to 2021
$1.1M
Overcoming explainability and data availability barriers to broad application of ECG ML screening with a system-wide ECG datasetR21HL172288 · NHLBI · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI STEINBERG, BENJAMIN ADAM, TASDIZEN, TOLGA · 2024 to 2025
$231k
NHLBI NIH HHS R21 HL172288NIBIB NIH HHS U24 EB029012NIGMS NIH HHS P41 GM103545NIGMS NIH HHS R24 GM136986
6 · The paper itself

Abstract

Ventricular arrhythmia frequently complicates myocardial ischemic events, sometimes to devastating ends. Accurate arrhythmia prediction in this setting could improve outcomes, yet traditional models struggle with the temporal complexity of the data. This study employs a Long Short-Term Memory (LSTM) network to predict the time to the next premature ventricular contraction (PVC) using high-resolution experimental data. We analyzed electrograms from 11 large animal experiments, identifying 1832 PVCs, and computed time-to-PVC. An LSTM model (247 inputs, 1024 hidden units) was trained on 10 experiments, with one held out for testing, achieving a validation MAE of 8.6 seconds and a test MAE of 135 seconds (loss 68.5). Scatter plots showed strong validation correlation and a positive test trend, suggesting the potential of this approach.

Identifiers

PMID41641225
PMCPMC12867102

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.