Evidence map›Paper›PMID 41641208›Full record

ArticleWorld journal of psychiatry2026

Predictive role of family dysfunction on psychological morbidity in breast cancer patients.

Zhi-Juan Li, Liang-Ying Chen, Xiu-Fen Zhuang, Pan-Pan Yang, Yan Fang

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Article in World journal of psychiatry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

5 authors.

Zhi-Juan LiDepartment of Head and Neck Oncology, Comprehensive Oncology, Affiliated Hospital of Jiangsu University, Zhenjiang 212001, Jiangsu Province, China.
Liang-Ying ChenDepartment of Hematology, Affiliated Hospital of Jiangsu University, Zhenjiang 212001, Jiangsu Province, China.
Xiu-Fen ZhuangDepartment of Head and Neck Oncology, Comprehensive Oncology, Affiliated Hospital of Jiangsu University, Zhenjiang 212001, Jiangsu Province, China.
Pan-Pan YangDepartment of Head and Neck Oncology, Comprehensive Oncology, Affiliated Hospital of Jiangsu University, Zhenjiang 212001, Jiangsu Province, China.
Yan FangDepartment of Head and Neck Oncology, Comprehensive Oncology, Affiliated Hospital of Jiangsu University, Zhenjiang 212001, Jiangsu Province, China. fangy813@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBreast cancer affects over 2.3 million women worldwide annually, with 30%-50% experiencing psychological morbidity, including anxiety and depression. Family functioning plays a crucial role in patients' psychological adaptation to cancer, yet the specific predictive relationship between family dysfunction dimensions and psychological outcomes remains insufficiently characterized. This study aimed to systematically examine how family dysfunction predicts psychological morbidity in breast cancer patients.

aimTo explore the predictive role of family dysfunction on psychological morbidity in breast cancer patients and develop a clinical risk prediction model.

methodsA retrospective cohort study was conducted among 285 breast cancer patients from June 2022 to March 2025 at a provincial tertiary hospital. Family functioning was assessed using the Family Assessment Device, and psychological health was evaluated using the Hospital Anxiety and Depression Scale. Univariate and multivariate logistic regression analyses were performed to identify predictive factors. A comprehensive risk prediction model was developed and validated.

resultsThe overall psychological morbidity rate was 41.5% (

conclusionFamily dysfunction significantly predicts psychological morbidity in breast cancer patients, with communication dysfunction being the most critical dimension. The developed risk prediction model demonstrates good accuracy for clinical decision-making.

Indexed as

AnxietyBreast cancerDepressionFamily dysfunctionPsychological morbidityRisk prediction

Identifiers

PMID41641208
PMCPMC12865462

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