ArticleCureus2026
Polyclonal Hypergammaglobulinemia in Severe Hidradenitis Suppurativa.
Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This is the case of a 36-year-old man with a 15-year history of Hurley stage III hidradenitis suppurativa (HS) who presented with painful nodules, chronic drainage, and extensive sinus tracts involving the axillae, groin, and gluteal cleft. The patient had previously failed multiple systemic and procedural therapies, including oral antibiotics, intralesional corticosteroids, adalimumab, and methotrexate. Physical examination demonstrated hypertrophic scarring, purulent discharge, and diffuse inflammatory activity. Laboratory evaluation revealed marked polyclonal hypergammaglobulinemia (pHGG), a finding whose association with HS is increasingly reported but remains incompletely understood. Therefore, we present an interesting case of severe, refractory HS with pHGG that improved after infliximab treatment, along with a brief discussion of relevant literature.
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