ArticleCureus2026
Acute Exacerbation of Chronic Periapical Pathology in a Dentist: An Autobiographical Case Report.
Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Acute exacerbations of chronic periapical pathology require prompt surgical or endodontic intervention, supported by pharmacotherapy. The role of analgesic selection, escalation, and rotation in acute dental pain remains underexplored. A 39-year-old male dentist with a 27-year history of trauma to the lower left central incisor presented with acute pain of three hours' duration. The tooth was non-vital with a stable periapical granuloma documented for over 15 years. Self-medication began with paracetamol, escalating to ibuprofen, aceclofenac, and etoricoxib, when pain worsened. Amoxicillin and metronidazole were also taken for infection control. On day three, endodontic access without anesthesia yielded minimal pus drainage but immediate pain relief. The canal was initially left open, then medicated with calcium hydroxide, and finally obturated with gutta-percha and zinc oxide-eugenol sealer. Three years of follow-up showed no recurrence. This case demonstrates symptom-driven analgesic escalation and de-escalation in an informed patient and raises the concept of analgesic rotation for reducing cumulative toxicity. While this may be relevant in chronic pain management, its role in acute odontogenic pain is limited, especially for agents with shared adverse profiles such as non-steroidal anti-inflammatory drugs (NSAIDs). Timely endodontic intervention remains the cornerstone of treatment for acute periapical abscesses. Analgesic prescribing should be individualized and symptom-based rather than fixed-duration, with rotation considered selectively.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.