Evidence map›Paper›PMID 41640841›Full record

ArticleFrontiers in physiology2025

Effects of GS-967, GS-6615 and ranolazine on the responses of the rabbit aorta to adrenergic nerve stimulation.

Maria Dolores Mauricio, Adrian Jorda, Solanye Guerra-Ojeda, Jose M Vila, Soraya L Valles, Martin Aldasoro

Abstract read
In one paragraph

Article in Frontiers in physiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Maria Dolores MauricioFaculty of Medicina, University of Valencia, Valencia, Spain.
Adrian JordaFaculty of Nursing and Podiatry, University of Valencia, Valencia, Spain.
Solanye Guerra-OjedaFaculty of Medicina, University of Valencia, Valencia, Spain.
Jose M VilaFaculty of Medicina, University of Valencia, Valencia, Spain.
Soraya L VallesFaculty of Medicina, University of Valencia, Valencia, Spain.
Martin AldasoroFaculty of Medicina, University of Valencia, Valencia, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: In the present study we aim to determine the effects of different inhibitors of the late sodium current (I Methods: The study was performed using specific inhibitors of I Results: Electrical Field Stimulation (EFS) (2, 4 and 8 Hz) induced frequency-dependent contractions that were abolished by tetrodotoxin, prazosin, or guanethidine (10 Discussion: These findings suggest distinct mechanisms of action among I

Indexed as

adrenergic nervous stimuliGS-6615GS-967late sodium currentnoradrenalineranolazine

Identifiers

PMID41640841
PMCPMC12864069

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.