Ultrasound-Activated Nanoplatform Counteracts Triple-Negative Breast Cancer via Remodeling Intratumoral Microbiota-Metabolism and Inducing Ferroptosis.

Shuao Li, Yuxiu Gao, Danni Jiang, Xiaoyu Wu, Yanan Feng, Fang Chen, Ningning He, Shangyong Li, Luxia Jing, Cheng Zhao

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Article in Biomaterials research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Shuao LiDepartment of Abdominal Ultrasound, The Affiliated Hospital of Qingdao University, Qingdao, Shandong 266003, China.

Yuxiu GaoDepartment of Abdominal Ultrasound, The Affiliated Hospital of Qingdao University, Qingdao, Shandong 266003, China.

Danni JiangDepartment of Abdominal Ultrasound, The Affiliated Hospital of Qingdao University, Qingdao, Shandong 266003, China.

Xiaoyu WuSchool of Basic Medicine, Qingdao Medical College, Qingdao University, Qingdao 266071, China.

Yanan FengDepartment of Abdominal Ultrasound, The Affiliated Hospital of Qingdao University, Qingdao, Shandong 266003, China.

Fang ChenDepartment of Abdominal Ultrasound, The Affiliated Hospital of Qingdao University, Qingdao, Shandong 266003, China.

Ningning HeSchool of Basic Medicine, Qingdao Medical College, Qingdao University, Qingdao 266071, China.

Shangyong LiDepartment of Abdominal Ultrasound, The Affiliated Hospital of Qingdao University, Qingdao, Shandong 266003, China.

Luxia JingDepartment of Abdominal Ultrasound, The Affiliated Hospital of Qingdao University, Qingdao, Shandong 266003, China.

Cheng ZhaoDepartment of Abdominal Ultrasound, The Affiliated Hospital of Qingdao University, Qingdao, Shandong 266003, China.ORCID https://orcid.org/0009-0002-7821-7755

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Triple-negative breast cancer (TNBC) remains therapeutically challenging owing to the paucity of broadly effective molecular targets. Piezoelectric nanomaterials that generate localized electric fields and reactive oxygen species under ultrasound (US) stimulation have emerged as a promising strategy for TNBC therapy. Here, we developed a US-activatable nanoplatform (HN-T/BT@Lip) in which toyocamycin-loaded CaCO

Identifiers

PMID41640714

DOI10.34133/bmr.0317

PMCPMC12864655

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