Evidence map›Paper›PMID 41640658›Full record

ReviewAdvanced biomedical research2025

Combination Therapy for the Treatment of Cutaneous Leishmaniasis Compared with Standard Drugs,

Parisa Mousavi, Azadeh Zolfaghari, Maryam Aghaei, Asieh Heidari, Zabihollah Shahmoradi, Seyed Hossein Hejazi

Abstract readReview
In one paragraph

Review in Advanced biomedical research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Parisa MousaviSkin Diseases and Leishmaniasis Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
Azadeh ZolfaghariSkin Diseases and Leishmaniasis Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
Maryam AghaeiSkin Diseases and Leishmaniasis Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
Asieh HeidariSkin Diseases and Leishmaniasis Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
Zabihollah ShahmoradiSkin Diseases and Leishmaniasis Research Center, Department of Dermatology, Isfahan University of Medical Sciences, Isfahan, Iran.
Seyed Hossein HejaziSkin Diseases and Leishmaniasis Research Center, Department of Parasitology and Mycology, Isfahan University of Medical Sciences, Isfahan, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The obligate intracellular parasite, Leishmania, causes leishmaniasis as an infectious disease. The parasite is transmitted through female sandfly bites and infects the host mononuclear phagocytes, leading to severe skin lesions and fatal systemic infection. The quick diagnosis and effective treatment can prevent the development scars and chronic or uncontrollable disease forms. The current chemical and physical treatments have limitations; hence, the use of plant compounds and their derivatives is a new proposed treatment method. Therefore, in this review, the recent advances in combination therapy of cutaneous leishmaniasis were investigated. The information was obtained from all articles published in PubMed, SciELO, ScienceDirect, Scopus, Google Scholar, and Web of Science databases (1998-2022). Search terms used were "Combination Therapy" AND "Cutaneous Leishmaniasis." The data showed increased synergistic efficacy or shortening the course of treatment and few adverse effects in the combined treatment of (CL),

Indexed as

Combination therapycutaneous leishmaniasisin vitroin vivo

Identifiers

PMID41640658
PMCPMC12867185

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.