Evidence map›Paper›PMID 41640624›Full record

ArticleBioinformatics advances2026

VST-DAVis: an R Shiny application and web-browser for spatial transcriptomics data analysis and visualization.

Sankarasubramanian Jagadesan, Chittibabu Guda

Abstract read
In one paragraph

Article in Bioinformatics advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Sankarasubramanian JagadesanDepartment of Genetics, Cell Biology and Anatomy, 985805 Nebraska Medical Center, University of Nebraska Medical Center, Omaha, NE 68198-5805, United States.
Chittibabu GudaDepartment of Genetics, Cell Biology and Anatomy, 985805 Nebraska Medical Center, University of Nebraska Medical Center, Omaha, NE 68198-5805, United States.ORCID https://orcid.org/0000-0002-5393-9316

Funding

UNMC Structural Biology CoreP20GM103427 · NIGMS · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI Heather Colleen Jensen-Smith · 2012 to 2026
$59.2M
UNMC/EPPLEY CANCER CENTER SUPPORT GRANTP30CA036727 · NCI · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI James Eudy · 1985 to 2026
$55.0M
NCI NIH HHS P30 CA036727NIGMS NIH HHS P20 GM103427
6 · The paper itself

Abstract

Summary: Visium HD Spatial Transcriptomics Data Analysis and Visualization (VST-DAVis) is an interactive, R Shiny application and web browser designed for intuitive analysis of spatial transcriptomics data generated using the 10x Genomics Visium HD platform. This user-friendly tool empowers researchers, particularly those without programming expertise, to perform end-to-end spatial transcriptomics analysis through a streamlined graphical interface. The platform is capable of handling both single and multiple samples, enabling comparative analyses across diverse biological conditions or replicates. It accepts various input formats including both H5 and matrix-based files from Space Ranger and outputs high-quality graphics from various visualization tools. VST-DAVis integrates several widely used R packages, such as Seurat, Monocle3, CellChat, and hdWGCNA, to offer a robust and flexible analytical environment that supports a wide range of analytical tasks, including quality control, clustering, marker gene identification, subclustering, trajectory inference, pathway enrichment analysis, cell-cell communication modeling, co-expression analysis, and transcription factor network reconstruction. By combining its analytical depth with user-friendliness, VST-DAVis makes advanced analyses accessible to various research communities that utilize spatial transcriptomics data. Availability and implementation: VST-DAVis is freely available at https://www.gudalab-rtools.net/VST-DAVis. It is implemented in R 4.5.2 and Bioconductor ≥ 3.22 using the Shiny framework and supports input from Space Ranger outputs. The source code and documentation are hosted on GitHub: https://github.com/GudaLab/VST-DAVis.

Identifiers

PMID41640624
PMCPMC12866912

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.