Evidence map›Paper›PMID 41640619›Full record

ArticleWorld journal of gastroenterology2026

Beyond anti-inflammatory strategies: Epigenetic targets as emerging therapeutic frontiers in acute pancreatitis.

Li-Ping Liang, Le Zhang, Dan-Dan Jin, Shao-Heng Zhang, Le Liu

Abstract readEditorial
PubMed Full text at PMC Publisher
In one paragraph

Article in World journal of gastroenterology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Li-Ping LiangDepartment of Gastroenterology and Hepatology, Guangzhou First People's Hospital, Guangzhou 510180, Guangdong Province, China.
Le ZhangDepartment of Gastroenterology, Zhujiang Hospital, Southern Medical University, Guangzhou 510280, Guangdong Province, China.
Dan-Dan JinDepartment of Gastroenterology, Zhujiang Hospital, Southern Medical University, Guangzhou 510280, Guangdong Province, China.
Shao-Heng ZhangDepartment of Gastroenterology, Zhujiang Hospital, Southern Medical University, Guangzhou 510280, Guangdong Province, China.
Le LiuShenzhen Clinical Research Center for Digestive Disease, Shenzhen Hospital, Southern Medical University, Shenzhen 518000, Guangdong Province, China. 1402744723@smu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute pancreatitis (AP) remains a challenging clinical condition with limited therapeutic options and high mortality rates in severe cases. Traditional anti-inflammatory approaches have shown disappointing results in clinical trials, highlighting the urgent need for novel therapeutic strategies targeting the underlying pathophysiological mechanisms. The study by Jia

Indexed as

Anti-Inflammatory AgentsEpigenesis, GeneticIndole AlkaloidsPancreatitisQuinazolinesAcute DiseaseAnimalsCeruletideDisease Models, AnimalEnhancer of Zeste Homolog 2 ProteinHumansMolecular Targeted TherapyOxidative StressPancreasQuinazolinonesRatsAnti-Inflammatory AgentsCeruletideEnhancer of Zeste Homolog 2 ProteinIndole AlkaloidsQuinazolinesQuinazolinonesrutecarpineAcute pancreatitisEpigenetic regulationEZH2FBXW11Rutaecarpine

Identifiers

PMID41640619
PMCPMC12865367

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.