Evidence map›Paper›PMID 41640605›Full record

ArticleWorld journal of gastroenterology2026

Gamma-glutamyl transferase as a redox-gatekeeper biomarker for pancreatic cystic neoplasms: A concise roadmap from epidemiology to bedside.

Ming-Qi Qiu, Ming-Min Chen, Wen-Jie Yang, Wu-Si Qiu

Abstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in World journal of gastroenterology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ming-Qi QiuSchool of Pharmacy, Inner Mongolia Medical University (Jinshan Campus), Hohhot 010110, Inner Mongolia Autonomous Region, China.
Ming-Min ChenDepartment of General Practice, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310009, Zhejiang Province, China.
Wen-Jie YangDepartment of Neurosurgery, The Affiliated Hospital of Hangzhou Normal University, Hangzhou 310015, Zhejiang Province, China.
Wu-Si QiuDepartment of Surgical Education and Research, Department of Neurosurgery, Affiliated Hospital of Hangzhou Normal University, Hangzhou 310015, Zhejiang Province, China. shihai954@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Serum gamma-glutamyl transferase (GGT), a marker of hepatobiliary and oxidative stress, emerged as a predictor of incident pancreatic cystic neoplasms (PCNs) in a 2.65-million nationwide cohort followed for > 10 years. The highest GGT quartile conferred 11% excess PCN risk, with hazard ratios rising across quartiles and persisting after 3- and 5-year lag exclusions. In redox-oncology, pancreatic

Indexed as

Biomarkers, TumorEarly Detection of Cancergamma-GlutamyltransferasePancreatic NeoplasmsCA-19-9 AntigenChromograninsCirculating Tumor DNACost-Benefit AnalysisGTP-Binding Protein alpha Subunits, GsHumansIncidenceOxidation-ReductionOxidative StressPancreasProto-Oncogene Proteins p21(ras)Risk FactorsBiomarkers, TumorCA-19-9 AntigenChromograninsCirculating Tumor DNAgamma-GlutamyltransferaseGGT1 protein, humanGNAS protein, humanGTP-Binding Protein alpha Subunits, GsKRAS protein, humanProto-Oncogene Proteins p21(ras)BiomarkerCohort studyEarly detectionGamma-glutamyl transferaseGNASKRASPancreatic cystic neoplasmRedox biology

Identifiers

PMID41640605
PMCPMC12865373

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.