SynthesisFrontiers in psychology2025
Efficacy of cognitive behavioral therapy for musculoskeletal pain: a systematic review and meta-analysis.
Synthesis in Frontiers in psychology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
4 citing papers in PubMed.
- Skill-Based Virtual Reality Therapy in High-Impact Chronic Pain: 2-Year Follow-Up Results From a Secondary Analysis of a Randomized Controlled Trial.Journal of medical Internet research · 2026Trial
- Comparative Efficacy of Non-invasive Brain Stimulation for Pain, Anxiety, and Depression: A Systematic Review and Network Meta-analysis.Pain and therapy · 2026Review
- Central Sensitization and Pain Catastrophizing Are More Strongly Associated with Health-Related Quality of Life than Bioelectrical Impedance Analysis-Derived Body-Composition Measures in Patients with Chronic Low Back Pain.Diagnostics (Basel, Switzerland) · 2026Article
- Impact of a digital mindfulness and motor imagery intervention on pain and perceived function in 203 patients with musculoskeletal pain.Frontiers in digital health · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Chronic musculoskeletal pain is a prevalent condition that causes substantial personal and societal burden, yet the effectiveness of non-pharmacological interventions remains debated. Cognitive behavioral therapy (CBT) and CBT-oriented cognitive-based interventions have been increasingly applied to pain management, but evidence has been fragmented across populations and treatment modalities. This study aimed to provide an updated synthesis of randomized controlled trials (RCTs) evaluating the efficacy of CBT for chronic musculoskeletal pain. Methods: We conducted a systematic search of PubMed, Web of Science, Scopus, Embase, PsycINFO, and the Cochrane Library. Eligible studies were screened according to predefined criteria, quality was assessed using the Cochrane Risk of Bias 2 tool (ROB 2.0) and statistical analyses were performed in Stata 15.1. Results: Fourteen high-quality RCTs involving 2,677 patients were included. Meta-analysis indicated that CBT significantly reduced pain catastrophizing (SMD = -0.77, 95% CI: -1.10 to -0.43, Conclusion: These findings suggest that CBT exerts consistent therapeutic benefits for chronic musculoskeletal pain, supporting its role as a reliable clinical non-pharmacological treatment option. Systematic review registration: This study protocol has been registered with the International Prospective Register of Systematic Reviews (PROSPERO) (registration number: CRD420251073898).
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.