Evidence map›Paper›PMID 41640573›Full record

ArticleMediators of inflammation2026

Threshold Effect of C-Reactive Protein-Albumin-Lymphocyte (CALLY) Index on Disease Activity in Rheumatoid Arthritis: Unveiling a Nonlinear Association.

Lina Leng, Quanyi Tang, Ying Li, Jinfeng Zhang, Yaorong Han, Xiaoli Li

Abstract read
In one paragraph

Article in Mediators of inflammation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Lina LengDepartment of Rheumatology, Xingtai People's Hospital, Xingtai, 054001, Hebei Province, China, xtrmyy.cn.ORCID https://orcid.org/0000-0003-0278-8535
Quanyi TangDepartment of Internal Medicine, Graduate School of Hebei Medical University, Shijiazhuang, 050017, Hebei Province, China, hebmu.edu.cn.
Ying LiDepartment of Oncology, 82 Group Hospital of Chinese People's Liberation Army, Baoding, 071000, Hebei Province, China.
Jinfeng ZhangDepartment of Rheumatology, Xingtai People's Hospital, Xingtai, 054001, Hebei Province, China, xtrmyy.cn.
Yaorong HanDepartment of Rheumatology, Xingtai People's Hospital, Xingtai, 054001, Hebei Province, China, xtrmyy.cn.
Xiaoli LiDepartment of Rheumatology, Xingtai People's Hospital, Xingtai, 054001, Hebei Province, China, xtrmyy.cn.ORCID https://orcid.org/0000-0002-7919-8691

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The relationship between the C-reactive protein (CRP)-albumin-lymphocyte (CALLY) index and disease activity of rheumatoid arthritis (RA) has not been explored at present. This study included 1058 RA patients and used a multiple linear regression model to evaluate the association between the CALLY index and 28 joint disease activity scores (DAS28) and further explored its potential nonlinear relationship using a two-stage segmented linear regression model. Multivariate adjusted analysis showed that CALLY was significantly negatively correlated with DAS28-erythrocyte sedimentation rate (ESR) (

Indexed as

AlbuminsArthritis, RheumatoidC-Reactive ProteinLymphocytesSerum AlbuminAdultAgedBlood SedimentationFemaleHumansLinear ModelsMaleMiddle AgedSeverity of Illness IndexAlbuminsC-Reactive ProteinSerum AlbuminbiomarkerC-reactive protein-albumin-lymphocyte indeximmunityinflammationnutritionalrheumatoid arthritis

Identifiers

PMID41640573
PMCPMC12866333

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.