Evidence map›Paper›PMID 41640543›Full record

ArticleAfrican health sciences2025

Inflammatory cytokines and quality of life response to weight reduction in obese patients with bronchial asthma.

Shehab M Abd E-Kader, Neveen Refaey, Afnan M AlKhateeb, Moataz Al-Madaah, Saad S AlFawaz, Ziyad A Neamatallah, Umar M Alabasi, Hajed Alotaibi, Mazen Homoud, Riziq Allah Mustafa Gaowgzeh and 10 more

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Article in African health sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Shehab M Abd E-KaderDepartment of Physical Therapy, Faculty of Medical Rehabilitation Sciences, King Abdulaziz University, Jeddah, Saudi Arabia.
Neveen RefaeyDepartment of Women Health, Faculty of Physical Therapy, Cairo University, Egypt.
Afnan M AlKhateebDepartment of Physical Therapy, Faculty of Medical Rehabilitation Sciences, King Abdulaziz University, Jeddah, Saudi Arabia.
Moataz Al-MadaahDepartment of Physical Therapy, Faculty of Medical Rehabilitation Sciences, King Abdulaziz University, Jeddah, Saudi Arabia.
Saad S AlFawazDepartment of Physical Therapy, Faculty of Medical Rehabilitation Sciences, King Abdulaziz University, Jeddah, Saudi Arabia.
Ziyad A NeamatallahDepartment of Physical Therapy, Faculty of Medical Rehabilitation Sciences, King Abdulaziz University, Jeddah, Saudi Arabia.
Umar M AlabasiDepartment of Physical Therapy, Faculty of Medical Rehabilitation Sciences, King Abdulaziz University, Jeddah, Saudi Arabia.
Hajed AlotaibiDepartment of Respiratory Therapy, Faculty of Medical Rehabilitation Sciences, King Abdulaziz University, Jeddah, Saudi Arabia.
Mazen HomoudDepartment of Respiratory Therapy, Faculty of Medical Rehabilitation Sciences, King Abdulaziz University, Jeddah, Saudi Arabia.
Riziq Allah Mustafa GaowgzehDepartment of Physical Therapy, Faculty of Medical Rehabilitation Sciences, King Abdulaziz University, Jeddah, Saudi Arabia.
Salwa R El-GendyDepartment of Physical Therapy, Faculty of Medical Rehabilitation Sciences, King Abdulaziz University, Jeddah, Saudi Arabia.
Mohamed F El-BannaDepartment of Physical Therapy, Faculty of Medical Rehabilitation Sciences, King Abdulaziz University, Jeddah, Saudi Arabia.
Heba EmbabyDepartment of Physical Therapy, Faculty of Medical Rehabilitation Sciences, King Abdulaziz University, Jeddah, Saudi Arabia.
Fatma A HegazyDepartment of Pediatrics, Faculty of Physical Therapy, Cairo University, Egypt.
Rasha M HegazyDepartment of Physical Therapy, Faculty of Medical Rehabilitation Sciences, King Abdulaziz University, Jeddah, Saudi Arabia.
Nahla KhalefaDepartment of Respiratory Therapy, Faculty of Medical Rehabilitation Sciences, King Abdulaziz University, Jeddah, Saudi Arabia.
Khaled M MounirFaculty of Physical Therapy, Galala University, Egypt.
Saif MehmedDepartment of Cardiopulmonary and Geriatrics, Faculty of Physical Therapy, Cairo University, Egypt.
Mohamed Y AbdelsameeDepartment of Basic Sciences, Faculty of Physical Therapy, Suez University, Egypt.
Ahmed M AboeleneenDepartment of Physical Therapy, Faculty of Medical Rehabilitation Sciences, King Abdulaziz University, Jeddah, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Globally, about 20% of the population are affected with asthma. However, public health is adversely affected with asthma and obesity. Objective: The target of the present study was to measure influence of weight loss on quality of life and Inflammatory cytokines of obese asthmatic patients. Material and Methods: Eighty obese asthmatic patients; the mean of their age was 42.71 ± 6.35 year and body mass index (BMI) was 32.85 ± 3.16 Kg/m2. Participants equally assigned in group (A) received weight reducing program, where group (B) received no therapeutic intervention. Results: The Health-related quality of life (SF-36 HRQL) subscale scores, interleukin-10 (IL-10) and Asthma Control Test (ACT) improved significantly, where, the mean values of BMI, TNF-α and IL-6 were significantly reduced in group (A). While group (B) had no significant changes in their parameters. In addition, the differences between both groups were not significant at the end of the study. Conclusion: Inflammatory cytokines and quality of life parameters improved with lifestyle modification among obese asthmatic patients.

Indexed as

AsthmaCytokinesObesityQuality of LifeWeight LossAdultBody Mass IndexFemaleHumansInterleukin-10Interleukin-6MaleMiddle AgedTreatment OutcomeTumor Necrosis Factor-alphaWeight Reduction ProgramsCytokinesInterleukin-10Interleukin-6Tumor Necrosis Factor-alphaBronchial AsthmaCytokinesObesityQuality of LifeWeight Reduction

Identifiers

PMID41640543
PMCPMC12865086

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.