Evidence map›Paper›PMID 41640527›Full record

ArticleAfrican health sciences2025

Antimicrobial susceptibility pattern of pathogens isolated from surgical wound infections in tertiary care hospitals of Pakistan.

Rashid Iqbal, Palwasha Ahmad, Zumaira Tahir

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Article in African health sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

3 authors.

Rashid IqbalDepartment of Health Sciences Technology, National Skills University, Islamabad, Pakistan.
Palwasha AhmadDepartment of Social Sciences and Humanities, Bahria University Islamabad, Pakistan.
Zumaira TahirShifa College of Medical Technology, Shifa Tameer-e-Milat University, Islamabad, Pakistan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Antimicrobial susceptibility testing for post-surgical site infections is crucial amid rising cases and antibiotic resistance. Objective: This study aimed to evaluate demographic factors, the occurrence of surgical wound site infections, pathogens associated with these infections, and antimicrobial susceptibility of the isolated pathogens. Subjects and Methods: A cross-sectional study including 384 patients suffering from post-surgical site infections was conducted in tertiary care hospitals in Pakistan over six months. Results: The study participants' ages ranged from 7 to 74 years old, with a mean age (±SD) of 30.4 (±9.5) years, and 44.8% of them were female. Among 384 study subjects, bacterial pathogens were isolated from 295 (76.80%). The frequency of gram-negative was 58.75%, whereas the frequency of gram-negative was 41.25%. Methicillin-resistant Staphylococcus aureus (MRSA), (19%), Staphylococcus aureus (Staph aureus) (18.0%), and Escherichia coli (E. coli) (18.0%) were the most common organisms isolated from wound infections. A significant association was present between occupation and culture sensitivity with a p-value of 0.01. Most of the culture-positive population had appendectomy site infection (92.90%). MRSA had the highest sensitivity to vancomycin (89.8%) and the highest resistance to gentamicin (85.7%). Staph. aureus was most sensitive to imipenem (80%) and most resistant to gentamicin (68.4%). E. coli was most sensitive to imipenem (100%) and most resistant to ceftazidime (90%). Conclusion: This study has provided a thorough description of the prevalence of gram-positive and gram-negative bacteria, as well as their relationships to wound type and demographic parameters.

Indexed as

Anti-Bacterial AgentsGram-Negative BacteriaGram-Positive BacteriaSurgical Wound InfectionAdolescentAdultAgedChildCross-Sectional StudiesDrug Resistance, BacterialFemaleHumansMaleMethicillin-Resistant Staphylococcus aureusMicrobial Sensitivity TestsMiddle AgedAnti-Bacterial AgentsThird Generation CephalosporinsAntibioticsgram-negativegram-positiveresistantsensitive

Identifiers

PMID41640527
PMCPMC12865059

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