Reliable and Accurate Differentiation of Optic Perineuritis and Optic Nerve Sheath Meningioma from the Radiologists' Perspective.

Onur Tuncer, Adam Baim, Michael Lee, Mehmet Gencturk, Can Özütemiz

Abstract read

In one paragraph

Article in Neuro-ophthalmology (Aeolus Press), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

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0 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Onur TuncerDepartment of Radiology, University of Minnesota Medical School, Minneapolis, Minnesota, USA.

Adam BaimDepartment of Ophthalmology, University of Minnesota Medical School, Minneapolis, Minnesota, USA.

Michael LeeDepartments of Ophthalmology and Visual Neurosciences, Neurology, and Neurosurgery, University of Minnesota Medical School, Minneapolis, Minnesota, USA.

Mehmet GencturkDepartment of Radiology, University of Minnesota Medical School, Minneapolis, Minnesota, USA.

Can ÖzütemizDepartment of Radiology, University of Minnesota Medical School, Minneapolis, Minnesota, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Optic perineuritis (OPN) and optic nerve sheath meningioma (ONSM) can present overlapping clinical and MRI findings. We aim to identify reliable MRI features to accurately differentiate between the two, ensuring timely optimal management. Patients diagnosed with OPN or ONSM were retrospectively selected. Two board-certified neuroradiologists independently reviewed contrast-enhanced, fat-saturated T1-weighted orbital MRI. Masked to patient information, they assessed nerve sheath contrast enhancement across optic nerve segments, quadrants, and intraconal fat, and measured maximum enhancing thickness (MET) and maximum enhancing length (MEL). Subsequently, they provided diagnoses based on their expertise. In a second run, controls were included, and they were allowed to see MRI order notes. Inter-rater agreements and diagnostic performances were calculated. We studied 35 patients with 41 pathological orbits. OPN had more bilateral involvement (

Indexed as

doughnut signOPNoptic nerve sheath meningiomaOptic perineuritistram-track sign

Identifiers

PMID41640500

DOI10.1080/01658107.2025.2542229

PMCPMC12867345

What OpenQuestion holds

Textmetadata

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.