ReviewPostepy dermatologii i alergologii2025
Chemical peeling in combination with microneedling versus chemical peeling or microneedling monotherapy in the treatment of acne scars: a systematic review and meta-analysis.
Review in Postepy dermatologii i alergologii, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Development and Optimization of Retinyl Palmitate-Loaded Oleogel and Nanoemulsion Designed with Potential for Microneedling Treatment.Pharmaceuticals (Basel, Switzerland) · 2026Article
- Microneedling Versus Chemical Peels for Atrophic Acne Scars: A Systematic Review and Meta-Analysis.Cureus · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Acne scars are a common and often distressing consequence of acne vulgaris, leading many patients to pursue aesthetic treatments. While microneedling and chemical peels are effective on their own, combining them may yield better results. Aim: To systematically evaluate the efficacy and safety of combining microneedling with chemical peeling versus either treatment alone in the management of atrophic acne scars. Material and methods: This systematic review and meta-analysis followed PRISMA 2020 guidelines and was registered in PROSPERO (CRD420251082268). A comprehensive search of PubMed, Embase, and Cochrane databases identified randomised and non-randomised trials comparing combined microneedling and chemical peeling to monotherapies. Outcomes included clinical improvement, patient satisfaction, adverse events, and quality-of-life measures. Results: Nine studies ( Conclusions: Combined microneedling and chemical peeling is superior to either treatment alone for atrophic acne scars, with favourable safety and patient-reported outcomes.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.