ArticleCase reports in medicine2026
Successful Treatment of Posttransplant Refractory Pure Red Cell Aplasia Following Parvovirus B19 Infection.
Article in Case reports in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Successful Treatment of Posttransplant Refractory Pure Red Cell Aplasia Following Parvovirus B19 Infection.Case reports in medicine · 2026Article
- Not Always 'Slapped Cheeks': Parvovirus B19 Infection Causing Severe Anaemia in a Kidney Transplant Recipient.Case reports in transplantation · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pure red cell aplasia (PRCA), a rare cause of anemia limited to the erythroid lineage, is characterized by normocytic normochromic anemia, severe reticulocytopenia, and markedly reduced or absent erythroid precursors in the bone marrow. We report a 44-year-old male with end-stage renal disease (ESRD) secondary to autosomal dominant polycystic kidney disease (ADPKD) who developed refractory PRCA following a live-donor renal transplant. One month posttransplant, the patient presented with severe, persistent anemia accompanied by fatigue and dyspnea. Initial management included blood transfusions, vitamin B12 supplementation, and adjustments to immunosuppressive therapy due to suspected drug-induced cytopenia. Bone marrow biopsy confirmed PRCA, and polymerase chain reaction (PCR) revealed a persistently elevated parvovirus B19 infection, a commonly recognized etiology of PRCA in immunocompromised patients. Treatment included intravenous immunoglobulin (IVIG) and frequent blood transfusions. Despite therapy, the patient experienced recurrent anemia, pancytopenia, and febrile neutropenia. Over successive hospitalizations, hematologic improvement was achieved with hemoglobin stabilization and significant viral load reduction. This case underscores the diagnostic and therapeutic complexity of managing parvovirus B19-induced PRCA in posttransplant patients, emphasizing the need for individualized strategies incorporating IVIG, supportive care, and tailored immunosuppressive regimens.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.