Evidence map›Paper›PMID 41640413›Full record

ArticleFrontiers in microbiology2025

Using molecular approaches to assess rabies virus diversity in Haiti and the Dominican Republic.

Rene E Condori, Augustin Pierre Dilius, Rolain Cadet, Griselda Lopez-Nuñez, Elinna Diaz-Mateo, Anna K Gomez-Belliard, Yasmeen B Ross, Cassandra Boutelle, Andres Velasco-Villa, Crystal M Gigante and 2 more

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Article in Frontiers in microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Rene E CondoriPoxvirus and Rabies Branch, Division of High Consequence Pathogens and Pathology, National Center for Emerging and Zoonotic Infectious Disease, Centers for Disease Control and Prevention, Atlanta, GA, United States.
Augustin Pierre DiliusMinistry of Agriculture, Port-au-Prince, Haiti.
Rolain CadetMinistry of Agriculture, Port-au-Prince, Haiti.
Griselda Lopez-NuñezLaboratorio Nacional de Salud Pública Dr. Defilló, Ministerio de Salud Pública y Asistencia Social, Santo Domingo, Dominican Republic.
Elinna Diaz-MateoCentro de Prevención y Control de Enfermedades Transmitidas por Vectores y Zoonosis (CECOVEZ), Ministerio de Salud Pública y Asistencia Social, Santo Domingo, Dominican Republic.
Anna K Gomez-BelliardDirección Provincial de Salud Santiago, Ministerio de Salud Pública y Asistencia Social, Santo Domingo, Dominican Republic.
Yasmeen B RossPoxvirus and Rabies Branch, Division of High Consequence Pathogens and Pathology, National Center for Emerging and Zoonotic Infectious Disease, Centers for Disease Control and Prevention, Atlanta, GA, United States.
Cassandra BoutellePoxvirus and Rabies Branch, Division of High Consequence Pathogens and Pathology, National Center for Emerging and Zoonotic Infectious Disease, Centers for Disease Control and Prevention, Atlanta, GA, United States.
Andres Velasco-VillaPoxvirus and Rabies Branch, Division of High Consequence Pathogens and Pathology, National Center for Emerging and Zoonotic Infectious Disease, Centers for Disease Control and Prevention, Atlanta, GA, United States.
Crystal M GigantePoxvirus and Rabies Branch, Division of High Consequence Pathogens and Pathology, National Center for Emerging and Zoonotic Infectious Disease, Centers for Disease Control and Prevention, Atlanta, GA, United States.
Yu LiPoxvirus and Rabies Branch, Division of High Consequence Pathogens and Pathology, National Center for Emerging and Zoonotic Infectious Disease, Centers for Disease Control and Prevention, Atlanta, GA, United States.
Ryan M WallacePoxvirus and Rabies Branch, Division of High Consequence Pathogens and Pathology, National Center for Emerging and Zoonotic Infectious Disease, Centers for Disease Control and Prevention, Atlanta, GA, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hispaniola, comprised of Haiti and the Dominican Republic, is a rabies-endemic island. Since 2013, Haiti and the Dominican Republic have operated advanced surveillance systems that have increased the number of humans and animals tested. In this study, rabies-positive samples collected between 2014 and 2023 were sequenced. Phylogenetic analysis revealed that the rabies virus (RABV) from Hispaniola forms a novel 'Caribbean subclade' with two distinct lineages: a major lineage associated with dogs and found across Haiti and parts of the Dominican Republic and a second lineage associated with dogs and mongoose found only in the Dominican Republic. Phylogenetic data support dogs as the main rabies reservoir in Haiti and show evidence of cross-border transmission. In the eastern part of the Dominican Republic, the evidence supports mongooses as the primary reservoir of rabies. Subclades within Haiti suggest that geospatial segregation of dogs and rabies may offer opportunities for zoned rabies elimination programs.

Indexed as

CaribbeanDominican RepublicHaitiphylogeneticrabies

Identifiers

PMID41640413
PMCPMC12864505

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.