Evidence map›Paper›PMID 41640143›Full record

ArticleProblemy endokrinologii2025

[Dual-energy CT for differential diagnosis of adrenal lesions].

N V Tarbaeva, A V Manaev, A Yu Kornelyuk, M V Godzenko, K V Ivaschenko, A Chevais, G A Melnichenkо, N G Mokrysheva

Abstract readEnglish Abstract
In one paragraph

Article in Problemy endokrinologii, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

N V TarbaevaEndocrinology Research Centre.
A V ManaevEndocrinology Research Centre.
A Yu KornelyukEndocrinology Research Centre.
M V GodzenkoEndocrinology Research Centre.
K V IvaschenkoEndocrinology Research Centre.
A ChevaisEndocrinology Research Centre.
G A MelnichenkоEndocrinology Research Centre.
N G MokryshevaEndocrinology Research Centre.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAdrenal lesion characterization remains a diagnostic challenge due to overlapping imaging features. Dual-energy CT (DECT) shows promise for identifying image-based biomarkers but requires further validation.

aimTo evaluate the diagnostic utility of DECT in differentiating adrenal lesions. MATERIALS AND

methodsThis retrospective single-center study analyzed DECT data. Parameters from 40/70/80 keV virtual monoenergetic images and water-iodine/fat-iodine/water-fat decomposition maps were evaluated. Statistical analysis included Kruskal-Wallis, Mann-Whitney U, ROC tests.

resultsThe cohort included 74 patients (median age 46.0 years (39.3-57.9), 48 women). For ACC and adenomas differentiation, mean 70 keV delayed phase attenuation showed the highest discriminative value (AUC=0.92; 95% CI: 0.81-1.00; p=0.001). For ACC and pheochromocytomas, standard deviation delayed phase water concentration (water-fat maps) achieved the highest diagnostic performance (AUC=0.89; 95% CI: 0.79-0.97; p=0.001). Maximum 70 keV delayed phase attenuation best distinguished adenomas from pheochromocytomas (AUC=0.82; 95% CI: 0.71-0.92; p<0.001).

conclusionDECT has proven its diagnostic value in the differential diagnosis of adrenal lesions.

Indexed as

AdenomaAdrenal Gland NeoplasmsPheochromocytomaTomography, X-Ray ComputedAdultDiagnosis, DifferentialFemaleHumansMaleMiddle AgedRetrospective Studies

Identifiers

PMID41640143
PMCPMC12954424

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