Evidence map›Paper›PMID 41639958›Full record

ArticleThe Journal of international medical research2026

Multi-omics analysis: Gut microbial metabolites in ovarian lesions.

Liu Yinghong, Yang Xiaojuan, Yang Xiaojuan

Abstract read
In one paragraph

Article in The Journal of international medical research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Liu YinghongDepartment of Rheumatology and Immunology, Chongqing Emergency Medical Center/Chongqing Fourth People's Hospital/Affiliated Central Hospital of Chongqing University, China.
Yang XiaojuanDepartment of Rheumatology and Immunology, Chongqing Emergency Medical Center/Chongqing Fourth People's Hospital/Affiliated Central Hospital of Chongqing University, China.ORCID 0009-0008-9145-6033
Yang XiaojuanDepartment of Rheumatology and Immunology, Chongqing Emergency Medical Center/Chongqing Fourth People's Hospital/Affiliated Central Hospital of Chongqing University, China.ORCID 0000-0003-1323-9478

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

ObjectiveThis study aimed to systematically elucidate the role of gut microbial metabolites in the development and progression of ovarian cancer.MethodsPublic databases, including GutMgene, were used to screen and integrate gut microbial metabolite-target genes with ovarian cancer-related genes, ultimately identifying 59 key intersection genes. A gut microbiota-metabolite-gene regulatory network was constructed, and Gene Ontology and Kyoto Encyclopedia of Genes and Genomes enrichment analyses, protein-protein interaction network analysis, and evaluations of the drug-likeness and toxicity of key metabolites were performed.ResultsA total of 72 key genes associated with immune regulation were identified. Enrichment analyses demonstrated that these genes were significantly involved in immune-related processes, including T cell activation and the Toll-like receptor signaling pathway. Protein-protein interaction network analysis identified five core genes:

Indexed as

Gastrointestinal MicrobiomeOvarian NeoplasmsFemaleGene Expression Regulation, NeoplasticGene Regulatory NetworksHumansMultiomicsProtein Interaction MapsSignal Transductiongut microbiotametabolitesOvarian cancerprotein interaction network

Identifiers

PMID41639958
PMCPMC12876636

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.